The DOI matches its Crossref record; 189 of the 189 references it cites were found in a registry or an index.
Macrophages in Atherosclerosis Regression
Open accessAbstract
Macrophages play a central role in the development of atherosclerotic cardiovascular disease (ASCVD), which encompasses coronary artery disease, peripheral artery disease, cerebrovascular disease, and aortic atherosclerosis. In each vascular bed, macrophages contribute to the maintenance of the local inflammatory response, propagate plaque development, and promote thrombosis. These central roles, coupled with their plasticity, makes macrophages attractive therapeutic targets in stemming the development of and stabilizing existing atherosclerosis. In the context of ASCVD, classically activated M1 macrophages initiate and sustain inflammation, and alternatively activated M2 macrophages resolve inflammation. However, this classification is now considered an oversimplification, and a greater understanding of plaque macrophage physiology in ASCVD is required to aid in the development of therapeutics to promote ASCVD regression. Reviewed herein are the macrophage phenotypes and molecular regulators characteristic of ASCVD regression, and the current murine models of ASCVD regression.
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1 retracted
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Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease
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Inflammation and atherosclerosis: signaling pathways and therapeutic intervention
Kong, P., Cui, Z.-Y., Huang, X.-F., Zhang, D.-D., Guo, R.-J., & Han, M. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-00955-7 · Cited by 1,183
Neuroprotective effect of SGLT2 inhibitors.
Pawlos, A., Broncel, M., Woźniak, E., & Gorzelak-Pabiś, P. (2021) · Molecules · doi:10.3390/molecules26237213 · Cited by 304
Sun, W., Xu, Y., Yao, Y., Yue, J., Wu, Z., Li, H., Shen, G., Liao, Y., Wang, H., & Zhou, W. (2022) · Journal of Nanobiotechnology · doi:10.1186/s12951-022-01296-x · Cited by 81
miR-223 Exerts Translational Control of Proatherogenic Genes in Macrophages
Nguyen, M.-A., Hoang, H.-D., Rasheed, A., Duchez, A.-C., Wyatt, H., Cottee, M. L., Graber, T. E., Susser, L., Robichaud, S., Berber, İ., et al. (2022) · Circulation Research · doi:10.1161/circresaha.121.319120 · Cited by 74
Matters of the heart: Cellular sex differences
Walker, C. J., Schroeder, M. E., Aguado, B. A., Anseth, K. S., & Leinwand, L. A. (2021) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2021.04.010 · Cited by 74
Metadata
- Authors
- Barrett, T. J.
- Venue
- Arteriosclerosis, Thrombosis, and Vascular Biology
- Published
- 2020-01
- Volume
- 40
- Issue
- 1
- Pages
- 20-33
- ISSN
- 1079-5642 (ISSN-L)
- 1524-4636
- OpenAlex
- W2988988674
- Cited by
- 628
- References
- 189
- FWCI
- 16.26
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
