Early Detection of Aortic Degeneration in a Mouse Model of Sporadic Aortic Aneurysm and Dissection Using Nanoparticle Contrast-Enhanced Computed Tomography

Ghaghada, Ketan B.; Ren, Pingping; Devkota, Laxman; Starosolski, Zbigniew; Zhang, Chen; Vela, Deborah; Stupin, Igor V.; Tanifum, Eric A.; Annapragada, Ananth V.; Shen, Ying H.; LeMaire, Scott A.

doi:10.1161/atvbaha.120.315210

Early Detection of Aortic Degeneration in a Mouse Model of Sporadic Aortic Aneurysm and Dissection Using Nanoparticle Contrast-Enhanced Computed Tomography

Objective: Early detection of aortic degeneration is critical for improving outcomes in patients with aortic aneurysm and dissection. We investigated nanoparticle contrast-enhanced computed tomography for the early detection of aortic injury. Approach and Results: In a mouse model of sporadic ao…