Innate Immune Pathway Links Obesity to Insulin Resistance
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The combination of overfeeding-induced obesity and inflammation (partly induced by the obesity itself) likely leads to diabetes.
“It is likely that it is the combination of overfeeding-induced obesity and inflammation (partly induced by the obesity itself [672]) that leads to diabetes [673].”
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References 20 · Cited by 31
- Authors
- Shah, P. K.
- Affiliations
- Cedars-Sinai Medical Center (US)
- Corresponding author
- Shah, Prediman K.
- ORCID
- Shah, Prediman K.
- Venue
- Circulation Research
- Published
- 2007-06-08
- Volume
- 100
- Issue
- 11
- Pages
- 1531-1533
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2159216974
- Cited by
- 31
- References
- 20
- Citations by year
- 2024: 1 · 2021: 1 · 2019: 2 · 2017: 2 · 2016: 3 · 2014: 3 · 2013: 1 · 2012: 5
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Health Sciences › Medicine › Physiology › Adipose Tissue and Metabolism
- Keywords
- innate immunity, obesity, insulin resistance, Toll-like receptors, adipose tissue inflammation
- MeSH terms
- Animals, Aorta, Dietary Fats, Disease Models, Animal, Humans, Immunity, Innate, Inflammation, Insulin Resistance, Mice, Inbred C57BL, Obesity, Signal Transduction, Palmitic Acid, Toll-Like Receptor 4, Mice
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