The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Microparticles, Vascular Function, and Atherothrombosis
Open accessAbstract
Membrane-shed submicron microparticles (MPs) are released after cell activation or apoptosis. High levels of MPs circulate in the blood of patients with atherothrombotic diseases, where they could serve as a useful biomarker of vascular injury and a potential predictor of cardiovascular mortality and major adverse cardiovascular events. Atherosclerotic lesions also accumulate large numbers of MPs of leukocyte, smooth muscle cell, endothelial, and erythrocyte origin. A large body of evidence supports the role of MPs at different steps of atherosclerosis development, progression, and complications. Circulating MPs impair the atheroprotective function of the vascular endothelium, at least partly, by decreased nitric oxide synthesis. Plaque MPs favor local inflammation by augmenting the expression of adhesion molecule, such as intercellular adhesion molecule -1 at the surface of endothelial cell, and monocyte recruitment within the lesion. In addition, plaque MPs stimulate angiogenesis, a key event in the transition from stable to unstable lesions. MPs also may promote local cell apoptosis, leading to the release and accumulation of new MPs, and thus creating a vicious circle. Furthermore, highly thrombogenic plaque MPs could increase thrombus formation at the time of rupture, together with circulating MPs released in this context by activated platelets and leukocytes. Finally, MPs also could participate in repairing the consequences of arterial occlusion and tissue ischemia by promoting postischemic neovascularization.
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Cites
Isolation of Putative Progenitor Endothelial Cells for Angiogenesis
Asahara, T., Murohara, T., Sullivan, A., Silver, M., van der Zee, R., Li, T., Witzenbichler, B., Schatteman, G., & Isner, J. M. (1997) · Science · doi:10.1126/science.275.5302.964 · Cited by 8,725
Inflammation in atherosclerosis
Libby, P. (2002) · Nature · doi:10.1038/nature01323 · Cited by 8,315
Inflammation in Atherosclerosis
Libby, P., Ridker, P. M., & Hansson, G. K. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.09.009 · Cited by 2,228
Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing
Sebbagh, M., Renvoizé, C., Hamelin, J., Riché, N., Bertoglio, J., & Bréard, J. (2001) · Nature Cell Biology · doi:10.1038/35070019 · Cited by 915
Willekens, F. L. A., Werre, J. M., Kruijt, J. K., Roerdinkholder-Stoelwinder, B., Groenen-Döpp, Y. A. M., van den Bos, A. G., Bosman, G. J. C. G. M., & van Berkel, T. J. C. (2005) · Blood · doi:10.1182/blood-2004-04-1578 · Cited by 280
Lactadherin Deficiency Leads to Apoptotic Cell Accumulation and Accelerated Atherosclerosis in Mice
Ait-Oufella, H., Kinugawa, K., Zoll, J., Simon, T., Boddaert, J., Heeneman, S., Blanc-Brude, O., Barateau, V., Potteaux, S., Merval, R., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.662080 · Cited by 255
Self-citationEnforced physical inactivity increases endothelial microparticle levels in healthy volunteers
Navasiolava, N. M., Dignat-George, F., Sabatier, F., Larina, I. M., Demiot, C., Fortrat, J.-O., Gauquelin-Koch, G., Kozlovskaya, I. B., & Custaud, M.-A. (2010) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00152.2010 · Cited by 99
Cited by
Mechanisms of plaque formation and rupture
Bentzon, J. F., Otsuka, F., Virmani, R., & Falk, E. (2014) · Circulation Research · doi:10.1161/circresaha.114.302721 · Cited by 2,391
Update on acute coronary syndromes: the pathologists' view
Falk, E., Nakano, M., Bentzon, J. F., Finn, A. V., & Virmani, R. (2013) · European Heart Journal · doi:10.1093/eurheartj/ehs411 · Cited by 1,047
Kalogeris, T., Baines, C. P., Krenz, M., & Korthuis, R. J. (2016) · Comprehensive Physiology · doi:10.1002/cphy.c160006 · Cited by 718
Emerging role of extracellular vesicles in inflammatory diseases
Buzas, E. I., György, B., Nagy, G., Falus, A., & Gay, S. (2014) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2014.19 · Cited by 677
Rho-associated coiled-coil containing kinases (ROCK): Structure, regulation, and functions
Julian, L., & Olson, M. F. (2014) · Small GTPases · doi:10.4161/sgtp.29846 · Cited by 550
Metadata
- Authors
- Rautou, P.-E., Vion, A.-C., Amabile, N., Chironi, G., Simon, A., Tedgui, A., & Boulanger, C. M.
- Venue
- Circulation Research
- Published
- 2011-08-19
- Volume
- 109
- Issue
- 5
- Pages
- 593-606
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2009135351
- Cited by
- 376
- References
- 7
- FWCI
- 14.11
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Rautou, P.-E., Vion, A.-C., Amabile, N., Chironi, G., Simon, A., Tedgui, A., & Boulanger, C. M. (2011). Microparticles, Vascular Function, and Atherothrombosis. Circulation Research. https://doi.org/10.1161/circresaha.110.233163
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
