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Cited by 452

The DOI matches its Crossref record; 149 of the 149 references it cites were found in a registry or an index.

Arrhythmogenic Cardiomyopathy

Open access
Corrado, Domenico, Basso, Cristina, Judge, Daniel P.·2017·Circulation Research

Abstract

Arrhythmogenic cardiomyopathy is an inherited heart muscle disorder, predisposing to sudden cardiac death, particularly in young patients and athletes. Pathological features include loss of myocytes and fibrofatty replacement of right ventricular myocardium; biventricular involvement is often observed. It is a cell-to-cell junction cardiomyopathy, typically caused by genetically determined abnormalities of cardiac desmosomes, which leads to detachment of myocytes and alteration of intracellular signal transduction. The diagnosis of arrhythmogenic cardiomyopathy does not rely on a single gold standard test but is achieved using a scoring system, which encompasses familial and genetic factors, ECG abnormalities, arrhythmias, and structural/functional ventricular alterations. The main goal of treatment is the prevention of sudden cardiac death. Implantable cardioverter defibrillator is the only proven lifesaving therapy; however, it is associated with significant morbidity because of device-related complications and inappropriate implantable cardioverter defibrillator interventions. Selection of patients who are the best candidates for implantable cardioverter defibrillator implantation is one of the most challenging issues in the clinical management.

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Crossref · 10.1161/circresaha.117.309345

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Metadata

Authors
Corrado, D., Basso, C., & Judge, D. P.
Venue
Circulation Research
Published
2017-09-15
Volume
121
Issue
7
Pages
784-802
ISSN
  • 0009-7330 (ISSN-L)
  • 1524-4571
OpenAlex
W4211192828
Cited by
452
References
149
FWCI
21.02
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Arrhythmogenic Cardiomyopathy. https://app.cochat.ai/papers/10.1161/circresaha.117.309345
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Corrado, D., Basso, C., & Judge, D. P. (2017). Arrhythmogenic Cardiomyopathy. Circulation Research. https://doi.org/10.1161/circresaha.117.309345

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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