Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis

Cochain, Clément, Vafadarnejad, Ehsan, Arampatzi, Panagiota, Pelisek, Jaroslav, Winkels, Holger, Ley, Klaus, Wolf, Dennis, Saliba, Antoine-Emmanuel +1 more·2018·Circulation Research

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  58. Pathophysiology of Atherosclerosis
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  59. Emerging technologies in metabolic and cardiovascular research
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