The DOI matches its Crossref record, with a small difference in title or year; 14 of the 14 references it cites were found in a registry or an index.
Perception of Atrial Fibrillation Before and After Radiofrequency Catheter Ablation: Relevance of Asymptomatic Arrhythmia Recurrence
Abstract
Background— The objective of this study was to assess the incidence and impact of asymptomatic arrhythmia in patients with highly symptomatic atrial fibrillation (AF) who qualified for radiofrequency (RF) catheter ablation. Methods and Results— In this prospective study, 114 patients with at least 3 documented AF episodes together with corresponding symptoms and an ineffective trial of at least 1 antiarrhythmic drug were selected for RF ablation. With the use of CARTO, circumferential lesions around the pulmonary veins and linear lesions at the roof of the left atrium and along the left atrial isthmus were placed. A continuous, 7-day, Holter session was recorded before ablation, right after ablation, and after 3, 6, and 12 months of follow-up. During each 7-day Holter monitoring, the patients recorded quality and duration of any complaints by using a detailed symptom log. More than 70 000 hours of ECG recording were analyzed. In the 7-day Holter records before ablation, 92 of 114 patients (81%) had documented AF episodes. All episodes were symptomatic in 35 patients (38%). In 52 patients (57%), both symptomatic and asymptomatic episodes were recorded, whereas in 5 patients (5%), all documented AF episodes were asymptomatic. After ablation, the percentage of patients with only asymptomatic AF recurrences increased to 37% ( P <0.05) at the 6-month follow-up. An analysis of patient characteristics and arrhythmia patterns failed to identify a specific subset who were at high risk for the development of asymptomatic AF. Conclusions— Even in patients presenting with highly symptomatic AF, asymptomatic episodes may occur and significantly increase after catheter ablation. A symptom-only–based follow-up would substantially overestimate the success rate. Objective measures such as long-term Holter monitoring are needed to identify asymptomatic AF recurrences after ablation.
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“Indeed, catheter ablation may increase the proportion of AF events that are asymptomatic, probably by alteration of cardiac neural element (Hindricks et al., 2005).”
From 2017 ISHNE-HRS expert consensus statement on ambulatory ECG and external cardiac monitoring/telemetry (2017) · cites this paper as Hindricks et al., 2005
Experimental — accuracy not yet measuredIn the citing paper
“Patient should also be aware that symptomatic and asymptomatic AF recurrences are frequent after catheter ablation.119,781,782”
From 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS (2016) · cites this paper as [119]
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Cites
Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins.
Haïssaguerre, M., Jaïs, P., Shah, D. C., Takahashi, A., Hocini, M., Quiniou, G., Garrigue, S., Mouroux, A. L., Métayer, P. L., & Clémenty, J. (1998) · New England Journal of Medicine · doi:10.1056/nejm199809033391003 · Cited by 8,040
Pappone, C., Santinelli, V., Manguso, F., Vicedomini, G., Gugliotta, F., Augello, G., Mazzone, P., Tortoriello, V., Landoni, G., Zangrillo, A., et al. (2004) · Circulation · doi:10.1161/01.cir.0000112641.16340.c7 · Cited by 1,018
Catheter Ablation for Paroxysmal Atrial Fibrillation
Oral, H., Scharf, C., Chugh, A., HALL, B. W., Cheung, P. W., Good, E. D., Veerareddy, S., Pelosi, F., & Morady, F. (2003) · Circulation · doi:10.1161/01.cir.0000095796.45180.88 · Cited by 896
Pappone, C., Rosanio, S., Augello, G., Gallus, G., Vicedomini, G., Mazzone, P., Gulletta, S., Gugliotta, F., Pappone, A., Santinelli, V., et al. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(03)00577-1 · Cited by 779
Page, R. L., Wilkinson, W. E., Clair, W. K., McCarthy, E. A., & Pritchett, E. L. (1994) · Circulation · doi:10.1161/01.cir.89.1.224 · Cited by 627 · cited 1×
“For patients with documented AF, the median total arrhythmia duration during the 7-day ECG periods measured 38 (10, 133) hours before ablation and postinterventionally declined to 36 (22, 79) hours immediately after ablation (P 0.”
BackgroundLong-term risk of recurrent atrial fibrillation as documented by an implantable monitoring device
Israel, C. W., Grönefeld, G., Ehrlich, J. R., Li, Y., & Hohnloser, S. H. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.08.027 · Cited by 478
Savelieva, I., & Camm, A. J. (2000) · Journal of Interventional Cardiac Electrophysiology · doi:10.1023/a:1009823001707 · Cited by 339
Kottkamp, H., Tanner, H., Kobza, R., Schirdewahn, P., Dorszewski, A., Gerds‐Li, J., Carbucicchio, C., Piorkowski, C., & Hindricks, G. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.04.049 · Cited by 196
Self-citationClinical Outcome after Radiofrequency Catheter Ablation of Focal Atrial Fibrillation Triggers
Gerstenfeld, E. P., Guerra, P. G., SPARKS, P. B., Hattori, K., & Lesh, M. D. (2001) · Journal of Cardiovascular Electrophysiology · doi:10.1046/j.1540-8167.2001.00900.x · Cited by 191
Asymptomatic or “Silent” Atrial Fibrillation
Page, R. L., Tilsch, T. W., Connolly, S. J., Schnell, D., Marcello, S. R., Wilkinson, W. E., & Pritchett, E. L. C. (2003) · Circulation · doi:10.1161/01.cir.0000051455.44919.73 · Cited by 165
Oral, H., Veerareddy, S., Good, E. D., HALL, B. W., Cheung, P. W., Tamirisa, K. P., Han, J. D., Fortino, J., Chugh, A., Bogun, F. M., et al. (2004) · Journal of Cardiovascular Electrophysiology · doi:10.1046/j.1540-8167.2004.04055.x · Cited by 119
Myocardial laser revascularization for the treatment of end-stage coronary artery disease
Saririan, M., & Eisenberg, M. J. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)02712-2 · Cited by 63
Berkowitsch, A. (2003) · EP Europace · doi:10.1016/s1099-5129(03)00089-8 · Cited by 45
Asymptomatic Atrial Fibrillation in Symptomatic Patients
Callans, D. J. (2004) · Journal of Cardiovascular Electrophysiology · doi:10.1046/j.1540-8167.2004.04345.x · Cited by 16
Research works printed but not linked: 1
- 10.1161/circ.89.1.8281651 · DOI
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Sorted by citations
Hindricks, G., Potpara, T., Dagres, N., Arbelo, E., Bax, J. J., Blomström‐Lundqvist, C., Boriani, G., Castella, M., Dan, G.-A., Dilaveris, P., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehaa612 · Cited by 10,550
Self-citation2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation
January, C. T., Wann, L. S., Alpert, J. S., Calkins, H. G., Cigarroa, J. E., Cleveland, J. C., CONTI, J. B., Ellinor, P. T., Ezekowitz, M. D., Field, M. E., et al. (2014) · Circulation · doi:10.1161/cir.0000000000000041 · Cited by 7,145
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P. F., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castellà, M., Diener, H., Heidbüchel, H., Hendriks, J., et al. (2016) · EP Europace · doi:10.1093/europace/euw295 · Cited by 6,438
Self-citation2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw210 · Cited by 6,418
Self-citationGuidelines for the management of atrial fibrillation
Authors/Task Force Members, Camm, A. J., Kirchhof, P. F., Lip, G. Y. H., Schotten, U., Savelieva, I., Ernst, S., Gelder, I. C. V., Al‐Attar, N., Hindricks, G., et al. (2010) · European Heart Journal · doi:10.1093/eurheartj/ehq278 · Cited by 5,924
Self-citation
Metadata
- Authors
- Hindricks, G., Piorkowski, C., Tanner, H., Kobza, R., Gerds-Li, J.-H., Carbucicchio, C., & Kottkamp, H.
- Affiliations
- Leipzig University (DE)
- From the Heart Center, Department of Electrophysiology, University of Leipzig, Leipzig, Germany.
- ORCID
- Venue
- Circulation
- Published
- 2005-07-19
- Volume
- 112
- Issue
- 3
- Pages
- 307-313
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W1988904908
- Cited by
- 506
- References
- 14
- Citations by year
- 2026: 9 · 2025: 11 · 2024: 9 · 2023: 11 · 2022: 14 · 2021: 14 · 2020: 15 · 2019: 20 · 2018: 15 · 2017: 18 · 2016: 19 · 2015: 17 · 2014: 34 · 2013: 28 · 2012: 37
- FWCI
- 27.35
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
- Keywords
- atrial fibrillation, asymptomatic atrial fibrillation, radiofrequency catheter ablation, atrial fibrillation recurrence, Holter monitoring, pulmonary vein isolation, antiarrhythmic drug failure, long-term follow-up
- MeSH terms
- Adrenergic beta-Antagonists, Adult, Aged, Anti-Arrhythmia Agents, Atrial Fibrillation, Atrial Flutter, Electrocardiography, Female, Heart Rate, Humans, Male, Middle Aged, Prospective Studies, Recurrence, Catheter Ablation
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