The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Novel Speckle-Tracking Radial Strain From Routine Black-and-White Echocardiographic Images to Quantify Dyssynchrony and Predict Response to Cardiac Resynchronization Therapy
Open accessAbstract
Background— Mechanical dyssynchrony is a potential means to predict response to cardiac resynchronization therapy (CRT). We hypothesized that novel echocardiographic image speckle tracking can quantify dyssynchrony and predict response to CRT. Methods and Results— Seventy-four subjects were studied: 64 heart failure patients undergoing CRT (aged 64±12 years, ejection fraction 26±6%, QRS duration 157±28 ms) and 10 normal controls. Speckle tracking applied to routine midventricular short-axis images calculated radial strain from multiple circumferential points averaged to 6 standard segments. Dyssynchrony from timing of speckle-tracking peak radial strain was correlated with tissue Doppler measures in 47 subjects ( r =0.94, P <0.001; 95% CI 0.90 to 0.96). The ability of baseline speckle-tracking radial dyssynchrony (time difference in peak septal wall–to–posterior wall strain ≥130 ms) to predict response to CRT was then tested. It predicted an immediate increase in stroke volume in 48 patients studied the day after CRT with 91% sensitivity and 75% specificity. In 50 patients with long-term follow-up 8±5 months after CRT, baseline speckle-tracking radial dyssynchrony predicted a significant increase in ejection fraction with 89% sensitivity and 83% specificity. Patients in whom left ventricular lead position was concordant with the site of latest mechanical activation by speckle-tracking radial strain had an increase in ejection fraction from baseline to a greater degree (10±5%) than patients with discordant lead position (6±5%; P <0.05). Conclusions— Speckle-tracking radial strain can quantify dyssynchrony and predict immediate and long-term response to CRT and has potential for clinical application.
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Recommendations for Quantitation of the Left Ventricle by Two-Dimensional Echocardiography
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The Effect of Cardiac Resynchronization on Morbidity and Mortality in Heart Failure
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Cardiac Resynchronization in Chronic Heart Failure
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CARDIAC RESYNCHRONIZATION IN CHRONIC HEART FAILURE
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Cited by
Normal Ranges of Left Ventricular Strain: A Meta-Analysis
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Cardiac-Resynchronization Therapy in Heart Failure with a Narrow QRS Complex
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Self-citationKhairy, P., Van Hare, G. F., Balaji, S., Berul, C. I., Cecchin, F., Cohen, M. I., Daniels, C. J., Deal, B. J., Dearani, J. A., Groot, N. D., et al. (2014) · Heart Rhythm · doi:10.1016/j.hrthm.2014.05.009 · Cited by 709
Targeted Left Ventricular Lead Placement to Guide Cardiac Resynchronization Therapy
Khan, F. Z., Virdee, M. S., Palmer, C. R., Pugh, P. J., O'Halloran, D., Elsik, M., Read, P. A., Begley, D., Fynn, S. P., & Dutka, D. P. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.12.030 · Cited by 647
Gorcsan, J., Abraham, T., Agler, D. A., Bax, J. J., Derumeaux, G., Grimm, R. A., Martin, R., Steinberg, J. S., Sutton, M. S. J., & Yu, C.-M. (2008) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2008.01.003 · Cited by 564
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Metadata
- Authors
- Suffoletto, M. S., Dohi, K., Cannesson, M., Saba, S., & Gorcsan, J.
- Venue
- Circulation
- Published
- 2006-02-21
- Volume
- 113
- Issue
- 7
- Pages
- 960-968
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2079861388
- Cited by
- 815
- References
- 36
- FWCI
- 59.93
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Suffoletto, M. S., Dohi, K., Cannesson, M., Saba, S., & Gorcsan, J. (2006). Novel Speckle-Tracking Radial Strain From Routine Black-and-White Echocardiographic Images to Quantify Dyssynchrony and Predict Response to Cardiac Resynchronization Therapy. Circulation. https://doi.org/10.1161/circulationaha.105.571455
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