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Cited by 246

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Left Ventricular Outflow Obstruction: Subaortic Stenosis, Bicuspid Aortic Valve, Supravalvar Aortic Stenosis, and Coarctation of the Aorta

Open access
Aboulhosn, Jamil, Child, John S.·2006·Circulation

Abstract

L eft ventricular outflow tract obstructions (LVOTOs) encompass a series of stenotic lesions starting in the anatomic left ventricular outflow tract (LVOT) and stretching to the descending portion of the aortic arch (Figure 1).Obstruction may be subvalvar, valvar, or supravalvar.These obstructions to forward flow may present alone or in concert, as in the frequent association of a bicuspid aortic valve with coarctation of the aorta.All of these lesions impose increased afterload on the left ventricle and, if severe and untreated, result in hypertrophy and eventual dilatation and failure of the left ventricle.LVOTOs are congenital in the vast majority of individuals younger than 50 years in the United States; some variants of subaortic obstruction are the exception.It is imperative to consider all patients with LVOTO at a high risk for developing infective endocarditis, and one should always institute appropriate measures for prophylaxis.The present article is intended as a contemporary review of the causes, manifestations, treatments, and outcomes of LVOTO; it will not address LVOTO in the pediatric population or genetic hypertrophic cardiomyopathy but will focus strictly on congenital malformations in the adult.

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Metadata

Authors
Aboulhosn, J., & Child, J. S.
Venue
Circulation
Published
2006-11-28
Volume
114
Issue
22
Pages
2412-2422
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
OpenAlex
W2163390732
Cited by
246
References
4
FWCI
6.42
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Left Ventricular Outflow Obstruction: Subaortic Stenosis, Bicuspid Aortic Valve, Supravalvar Aortic Stenosis, and Coarctation of the Aorta. https://app.cochat.ai/papers/10.1161/circulationaha.105.592089
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Aboulhosn, J., & Child, J. S. (2006). Left Ventricular Outflow Obstruction: Subaortic Stenosis, Bicuspid Aortic Valve, Supravalvar Aortic Stenosis, and Coarctation of the Aorta. Circulation. https://doi.org/10.1161/circulationaha.105.592089

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