Cited by 273Peripheral Artery Disease ManagementCardiovascular Health and Risk FactorsDiabetic Foot Ulcer Assessment and Management

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Gaps in Public Knowledge of Peripheral Arterial Disease: The First National PAD Public Awareness Survey

Hirsch, Alan T., Murphy, Timothy P., Lovell, Marge B., Twillman, Gwen, Treat-Jacobson, Diane, Harwood, Eileen M., Mohler, Emile R., Creager, Mark A., Hobson, Robert W., Robertson, Rose Marie, Howard, W. James, Schroeder, Paul, Criqui, Michael H.·2007·Circulation

DOI 10.1161/circulationaha.107.725101

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Abstract

Background— Lower-extremity peripheral arterial disease (PAD) is associated with decreased functional status, diminished quality of life, amputation, myocardial infarction, stroke, and death. Nevertheless, public knowledge of PAD as a morbid and mortal disease has not been previously assessed. Methods and Results— We performed a cross-sectional, population-based telephone survey of a nationally representative sample of 2501 adults ≥50 years of age, with oversampling of blacks and Hispanics. The survey instrument measured the demographic, risk factor, and cardiovascular disease characteristics of the study population; prevalent leg symptoms; PAD awareness relative to atherosclerosis risk factors and other cardiovascular and noncardiovascular diseases; perceived causes of PAD; and perceived systemic and limb consequences of PAD. Respondents were 67.2±12.6 years of age with a high prevalence of risk factors but only a modest burden of known coronary or cerebrovascular disease. Twenty-six percent of respondents expressed familiarity with PAD, a rate significantly lower than that for any other cardiovascular disease or atherosclerosis risk factor. Within the “PAD-aware” cohort, knowledge was poor. Half of these individuals were not aware that diabetes and smoking increase the risk for PAD; 1 in 4 knew that PAD is associated with increased risk of heart attack and stroke; and only 14% were aware that PAD could lead to amputation. All knowledge domains were lower in individuals with lower income and education levels. Conclusions— The public is poorly informed about PAD, with major knowledge gaps regarding the definition of PAD, risk factors that lead to PAD, and associated limb symptoms and amputation risk. The public is not aware that PAD imposes a high short-term risk of heart attack, stroke, and death. For the national cardiovascular disease burden to be reduced, public PAD knowledge could be improved by national PAD public education programs designed to reduce critical knowledge gaps.

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10.1161/circ.81.2.2404633 · DOI
10.1161/circ.71.3.3156006 · DOI
NHLBI Workshop on Peripheral Arterial Disease (PAD): Developing a Public Awareness Campaign Meeting Summary. Bethesda Md: US Department of Health and Human Services National Institutes of Health National Heart Lung and Blood Institute; 2003.
10.1161/hyp.26.1.60 · DOI

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Improving Peripheral Artery Disease Outcomes Requires Interventions at the Patient, Healthcare Team, and Healthcare System Levels
Shahoud, M., Cheever, C. R., Browder, S. E., Johnson, J. K., McGinigle, K. L., & Mihas, P. (2026) · JVS-Vascular Insights · doi:10.1016/j.jvsvi.2026.100546

Authors: Hirsch, A. T., Murphy, T. P., Lovell, M. B., Twillman, G., Treat-Jacobson, D., Harwood, E. M., Mohler, E. R., Creager, M. A., Hobson, R. W., Robertson, R. M., Howard, W. J., Schroeder, P., & Criqui, M. H.
Affiliations: University of Minnesota (US)
From the Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis (A.T.H., E.M.H.); Minneapolis Heart Institute Foundation, Minneapolis, Minn (A.T.H.); Rhode Island Hospital and Lifespan, Inc, Providence (T.P.M.); Division of Vascular Surgery, London Health Sciences Center, London, Ontario, Canada (M.B.L.); Peripheral Arterial Disease Coalition, Washington, DC (G.T.); University of Minnesota School of Nursing, Minneapolis (D.T.-J.); University of...
Corresponding author: Hirsch, Alan T.
ORCID: Murphy, Timothy P.
Harwood, Eileen M.
Creager, Mark A.
Robertson, Rose Marie
Criqui, Michael H.
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2007-10-30
Volume: 116
Issue: 18
Pages: 2086-2094
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/circulationaha.107.725101
OpenAlex: W2120827920
Semantic Scholar: 4d0f333b1d5b9eda793adabe9d5315707a7b95fa
Cited by: 273
References: 37
Citations by year: 2026: 10 · 2025: 12 · 2024: 16 · 2023: 22 · 2022: 17 · 2021: 17 · 2020: 14 · 2019: 14 · 2018: 10 · 2017: 8 · 2016: 18 · 2015: 6 · 2014: 13 · 2013: 13 · 2012: 18
FWCI: 16.61
Type: journal article
Language: en
Open access: closed
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
Funders: Bristol-Myers Squibb
Pfizer
AstraZeneca
GlaxoSmithKline
Sanofi
Boston Scientific Corporation
Otsuka America
National Institutes of Health
Abbott Vascular
National Heart, Lung, and Blood Institute
Topics: Health Sciences › Medicine › Surgery › Peripheral Artery Disease Management
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetic Foot Ulcer Assessment and Management
Keywords: peripheral arterial disease, public awareness, health knowledge gaps, atherosclerosis risk factors, diabetes mellitus, smoking, amputation risk, stroke risk, myocardial infarction risk, lower extremity symptoms, socioeconomic disparities, health education
MeSH terms: Adult, Aged, Aged, 80 and over, Awareness, Cross-Sectional Studies, Female, Humans, Health Knowledge, Attitudes, Practice, Male, Middle Aged, Risk Factors, United States, Peripheral Vascular Diseases

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Gaps in Public Knowledge of Peripheral Arterial Disease: The First National PAD Public Awareness Survey

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