Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 474

The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.

Perioperative Myocardial Infarction

Open access
Landesberg, Giora, Beattie, W. Scott, Mosseri, Morris, Jaffe, Allan S., Alpert, Joseph S.·2009·Circulation

Abstract

M ore than 230 million major surgeries are performed annually worldwide, 1 and this number grows continuously.The 30-day mortality associated with moderate-to high-risk noncardiac surgery in recent large cohorts and population-based studies exceeds 2% 2-4 and surpasses 5% in patients at high cardiac risk.5 Cardiac complications constitute the most common cause of postoperative morbidity and mortality, 4,6 having considerable impact on the length and cost of hospitalization.7 As our population ages, more high-risk cardiac patients will undergo surgery, and perioperative myocardial infarction (PMI) can be an increasing problem. Redefinition of PMITraditionally, MI was defined by the World Health Organization criteria, ECG criteria, and cardiac enzymes.Defining PMI, however, is often difficult because most PMIs occur without symptoms in anesthetized or sedated patients, ECG changes are subtle and/or transient, and the creatine kinase-MB isoenzyme has limited sensitivity and specificity because of coexisting skeletal muscle injury.8 Consequently, PMI was often recognized late (postoperative day 3 to 5), resulting in high (30% to 70% 9 ) mortality.Cardiac troponin assays have changed this definition.10 The recent universal definition of MI 11 is based on a rise and/or fall of cardiac biomarkers (preferably troponin) in the setting of myocardial ischemia: cardiac symptoms, ECG changes, or imaging findings.Studies using serial troponin measurements demonstrate that most PMIs start within 24 to 48 hours of surgery during the greatest postoperative stress.[12][13][14][15] Le Manach et al 15 observed early (Ͻ24 hours) and late (Ͼ24 hours) peaks in troponin in 1136 patients after abdominal aortic aneurysmectomy.Yet, 90% of troponin elevations began within Ͻ24 hours. PathophysiologyTwo distinct mechanisms may lead to PMI: acute coronary syndrome and prolonged myocardial oxygen supply-demand imbalance in the presence of stable coronary artery disease (CAD), designated type 1 and type 2 by the universal definition of MI. 11 This distinction is key to therapeutic considerations.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1161/circulationaha.108.828228

Cites

83 of 83 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 83 references

Cited by

See all 474

Metadata

Authors
Landesberg, G., Beattie, W. S., Mosseri, M., Jaffe, A. S., & Alpert, J. S.
Venue
Circulation
Published
2009-06-09
Volume
119
Issue
22
Pages
2936-2944
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
OpenAlex
W2164470751
Cited by
474
References
83
FWCI
14.83
Type
journal article
Language
en
Open access
bronze

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Perioperative Myocardial Infarction. https://app.cochat.ai/papers/10.1161/circulationaha.108.828228
The paper
Landesberg, G., Beattie, W. S., Mosseri, M., Jaffe, A. S., & Alpert, J. S. (2009). Perioperative Myocardial Infarction. Circulation. https://doi.org/10.1161/circulationaha.108.828228

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.