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Race/Ethnicity, Quality of Care, and Outcomes in Ischemic Stroke
Open accessAbstract
Background— Prior studies suggest differences in stroke care associated with race/ethnicity. We sought to determine whether such differences existed in a population of black, Hispanic, and white patients hospitalized with stroke among hospitals participating in a quality-improvement program. Methods and Results— We analyzed in-hospital mortality and 7 stroke performance measures among 397 257 patients admitted with ischemic stroke to 1181 hospitals participating in the Get With The Guidelines-Stroke program 2003 through 2008. Relative to white patients, black and Hispanic patients were younger and more often had diabetes mellitus and hypertension. After adjustment for both patient- and hospital-level variables, black patients had lower odds relative to white patients of receiving intravenous thrombolysis (odds ratio [OR], 0.84; 95% confidence interval [CI], 0.77 to 0.91), deep vein thrombosis prophylaxis (OR, 0.88; 95% CI, 0.83 to 0.92), smoking cessation (OR, 0.85; 95% CI, 0.79 to 0.91), discharge antithrombotics (OR, 0.88; 95% CI, 0.84 to 0.92), anticoagulants for atrial fibrillation (OR, 0.84; 95% CI, 0.75 to 0.94), and lipid therapy (OR, 0.91; 95% CI, 0.88 to 0.96), and of dying in-hospital (OR, 0.90; 95% CI, 0.85 to 0.95). Hispanic patients received similar care as their white counterparts on all 7 measures and had similar in-hospital mortality. Black (OR, 1.31; 95% CI, 1.28 to 1.35) and Hispanic (OR, 1.16; 95% CI, 1.11 to 1.20) patients had higher odds of exceeding the median length of hospital stay relative to whites. During the study, quality of care improved in all 3 race/ethnicity groups. Conclusions— Black patients with stroke received fewer evidence-based care processes than Hispanic or white patients. These differences could lead to increased risk of recurrent stroke. Quality of care improved substantially in the Get With The Guidelines-Stroke Program over time for all 3 racial/ethnic groups.
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“This racial profile is similar to existing studies in stroke but reflects issues with equity of access, considering the well-documented health inequalities in stroke.30,31”
From Wellbeing After Stroke (WAterS): Feasibility Testing of a Co-developed Acceptance and Commitment Therapy Intervention to Support Psychological Adjustment After Stroke. (2024) · cites this paper as [30]
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Advances in stroke care and research in 2010
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Tørnes, M., McLernon, D. J., Bachmann, M. O., Musgrave, S. D., Warburton, E. A., Potter, J. F., & Myint, P. K. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-024506 · Cited by 9
How Patient Demographics, Imaging, and Beliefs Influence Tissue-Type Plasminogen Activator Use
Shamy, M. C. F., Pugliese, M., Meisel, K. M., Rodriguez, R. A., Kim, A. S., Stahnisch, F. W., & Smith, E. E. (2016) · Stroke · doi:10.1161/strokeaha.116.013344 · Cited by 8
Self-citationRacial and Ethnic Disparities in Stroke Reperfusion Therapy in the USA
Faigle, R. (2023) · Neurotherapeutics · doi:10.1007/s13311-023-01388-y · Cited by 9
Was COVID‐19 Associated With Worsening Inequities in Stroke Treatment and Outcomes?
Glance, L. G., Benesch, C. G., Maddox, K. E. J., Bender, M. T., Shang, J., Stone, P. W., Lustik, S. J., Nadler, J. W., Galton, C., & Dick, A. W. (2023) · Journal of the American Heart Association · doi:10.1161/jaha.123.031221 · Cited by 8
Considerations and strategies for educating stroke patients with neurological deficits
Griffin, L. J., & Hickey, J. V. (2013) · Journal of Nursing Education and Practice · doi:10.5430/jnep.v3n8p125 · Cited by 8
Albright, K. C., Boehme, A. K., Tanner, R. M., Blackburn, J. L., Howard, G., Howard, V. J., Safford, M. M., Beasley, M., & Limdi, N. A. (2016) · Ethnicity & Disease · doi:10.18865/ed.26.1.9 · Cited by 8
No Racial Disparity in Outcome Measures After Endovascular Treatment for Stroke in the Elderly
Mohammaden, M. H., Haussen, D. C., Pisani, L., Al‐Bayati, A. R., Bianchi, N. A., Liberato, B. B., Bhatt, N., Frankel, M., & Nogueira, R. G. (2021) · Stroke · doi:10.1161/strokeaha.120.033537 · Cited by 8
Self-citationNakagawa, K., Ito, C. S., & King, S. L. (2016) · Stroke · doi:10.1161/strokeaha.116.014618 · Cited by 8
Jones, K., Bhattacharjee, R., Krishnamurthi, R., Blanton, S., Barker-Collo, S. L., Theadom, A., Thrift, A. G., Wolf, S. L., Venketasubramanian, N., Parmar, P. G. K., et al. (2018) · Clinical Rehabilitation · doi:10.1177/0269215518777565 · Cited by 8
Gardener, H. E., Rundek, T., Lichtman, J. H., Leifheit, E. C., Wang, K., Asdaghi, N., Romano, J. G., & Sacco, R. L. (2021) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2020.105586 · Cited by 7
Atrial Fibrillation and Retinal Stroke
Lusk, J. B., Nalawade, V. V., Wilson, L. E., Song, A., Schrag, M., Biousse, V., Dumitrașcu, O., Poli, S., Piccini, J. P., Hammill, B. G., et al. (2025) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.53819 · Cited by 7
Impact of Day of the Week and Time of Arrival on Ischemic Stroke Management.
Rodríguez-Rivera, I. V., Santiago, F. L., Estapé, E. S., González‐Sepúlveda, L., & Brau, R. H. (2015) · PubMed · Cited by 7
Measuring and Changing the Quality of Care via National Registries
Schwamm, L. H. (2013) · Stroke · doi:10.1161/strokeaha.111.000049 · Cited by 7
Self-citationWu, Y., Xirasagar, S., Nan, Z., Heidari, K., & Sen, S. (2023) · Medical Care · doi:10.1097/mlr.0000000000001926 · Cited by 7
Urdaneta, A. E., Fisk, C., Tandel, M. D., García, A., & Govindarajan, P. (2023) · Air Medical Journal · doi:10.1016/j.amj.2023.06.007 · Cited by 6
WANG, J. J., Katz, J. M., Sanmartin, M. X., Naidich, J. J., Rula, E. Y., & Sanelli, P. C. (2023) · Journal of the American College of Radiology · doi:10.1016/j.jacr.2023.07.015 · Cited by 6
Factors Influencing Acute Stroke Thrombolytic Treatments in Hispanics In the San Diego Region.
Chen, P. M., Nguyen, D., Ho, J. P., Pirastehfar, M., Narula, R., Rapp, K. S., Agrawal, K., Huisa, B. N., Modir, R., Meyer, D. M., et al. (2018) · PubMed · Cited by 6
Feldman, P. H., McDonald, M. V., Onorato, N., Stein, J. M., & Williams, O. A. (2022) · Pilot and Feasibility Studies · doi:10.1186/s40814-022-00979-4 · Cited by 5
Patient, carer and health worker perspectives of stroke care in New Zealand: a mixed methods survey
Thompson, S. G., Levack, W., Douwes, J. E., Girvan, J., Abernethy, G., Barber, P. A., Fink, J., Gommans, J., Davis, A., Harwood, M. L. N., et al. (2022) · Disability and Rehabilitation · doi:10.1080/09638288.2022.2117862 · Cited by 5
Hart, S. L., Howard, G., Cummings, D. M., Albright, K. C., Reis, P. J., & Howard, V. J. (2024) · Neurology · doi:10.1212/wnl.0000000000209200 · Cited by 5
Otite, F. O., & Morris, N. A. (2024) · Critical Care Clinics · doi:10.1016/j.ccc.2024.05.006 · Cited by 8
Mejia, N. I., & Nardin, R. A. (2010) · Neurology · doi:10.1212/wnl.0b013e3181f25f44 · Cited by 5
Kenton Award Lecture—Stroke Disparities Research: Learning From the Past, Planning for the Future
Kapral, M. K. (2023) · Stroke · doi:10.1161/strokeaha.122.039562 · Cited by 6
Metadata
- Authors
- Schwamm, L. H., Reeves, M. J., Pan, W., Smith, E. E., Frankel, M. R., Olson, D., Zhao, X., Peterson, E., & Fonarow, G. C.
- Affiliations
- Emory University (US)
- ORCID
- Venue
- Circulation
- Published
- 2010-04-06
- Volume
- 121
- Issue
- 13
- Pages
- 1492-1501
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2074386052
- Cited by
- 292
- References
- 42
- Citations by year
- 2026: 8 · 2025: 21 · 2024: 29 · 2023: 26 · 2022: 17 · 2021: 19 · 2020: 10 · 2019: 11 · 2018: 8 · 2017: 18 · 2016: 19 · 2015: 20 · 2014: 17 · 2013: 23 · 2012: 13
- FWCI
- 15.94
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Heart Association
- Pfizer
- American Stroke Association
- Centers for Disease Control and Prevention
- National Institute of Neurological Disorders and Stroke
- Topics
- Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cerebrovascular and Carotid Artery Diseases
- Keywords
- ischemic stroke, racial disparities, ethnic disparities, quality of care, Black patients, Hispanic patients, Caucasian patients, intravenous thrombolysis, deep vein thrombosis prevention, smoking cessation, antithrombotic therapy, atrial fibrillation anticoagulation, lipid therapy, in-hospital mortality, length of hospital stay, Get With The Guidelines-Stroke, evidence-based care
- MeSH terms
- Aged, Aged, 80 and over, Black or African American, Brain Ischemia, Female, Hispanic or Latino, Humans, Male, Middle Aged, Quality of Health Care, Registries, Risk Factors, United States, Thrombolytic Therapy, Hospital Mortality, Stroke, Black People, White People, Racial Groups
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