The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Relationship Between Intravascular Ultrasound Guidance and Clinical Outcomes After Drug-Eluting Stents: The Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents (ADAPT-DES) Study
Abstract
Background—: Prior small to modest-sized studies suggest a benefit of intravascular ultrasound (IVUS) guidance in noncomplex lesions. Whether IVUS guidance is associated with improved clinical outcomes after drug-eluting stent (DES) implantation in an unrestricted patient population is unknown. Methods and Results—: Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents (ADAPT-DES) was a prospective, multicenter, nonrandomized “all-comers” study of 8583 consecutive patients at 11 international centers designed to determine the frequency, timing, and correlates of stent thrombosis and adverse clinical events after DES. Propensity-adjusted multivariable analysis was performed to examine the relationship between IVUS guidance and 1-year outcomes. IVUS was utilized in 3349 patients (39%), and larger-diameter devices, longer stents, and/or higher inflation pressures were used in 74% of IVUS-guided cases. IVUS guidance compared with angiography guidance was associated with reduced 1-year rates of definite/probable stent thrombosis (0.6% [18 events] versus 1.0% [53 events]; adjusted hazard radio, 0.40; 95% confidence interval, 0.21–0.73; P =0.003), myocardial infarction (2.5% versus 3.7%; adjusted hazard radio, 0.66; 95% confidence interval, 0.49–0.88; P =0.004), and composite adjudicated major adverse cardiac events (ie, cardiac death, myocardial infarction, or stent thrombosis) (3.1% versus 4.7%; adjusted hazard radio, 0.70; 95% confidence interval, 0.55–0.88; P =0.002). The benefits of IVUS were especially evident in patients with acute coronary syndromes and complex lesions, although significant reductions in major adverse cardiac events were present in all patient subgroups those with including stable angina and single-vessel disease. Conclusions—: In ADAPT-DES, the largest study of IVUS use to date, IVUS guidance was associated with a reduction in stent thrombosis, myocardial infarction, and major adverse cardiac events within 1 year after DES implantation. Clinical Trial Registration—: URL: http://www.clinicaltrials.gov . Unique identifier: NCT00638794.
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Cites
Clinical End Points in Coronary Stent Trials: A Case for Standardized Definitions
Cutlip, D. E., Windecker, S., Mehran, R., Boam, A., Cohen, D. J., van Es, G.-A., Gabriel Steg, P., Morel, M.-A., Mauri, L., Vranckx, P., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.685313 · Cited by 5,497
Self-citationStone, G. W., Witzenbichler, B., Weisz, G., Rinaldi, M. J., Neumann, F.-J., Metzger, D. C., Henry, T. D., Cox, D. A., Duffy, P. L., Mazzaferri, E., et al. (2013) · The Lancet · doi:10.1016/s0140-6736(13)61170-8 · Cited by 857
Self-citationBangalore, S., Kumar, S., Fusaro, M., Amoroso, N., Attubato, M. J., Feit, F., Bhatt, D. L., & Slater, J. (2012) · Circulation · doi:10.1161/circulationaha.112.097014 · Cited by 574
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Bare metal stent restenosis is not a benign clinical entity
Chen, M. S., John, J. M., Chew, D. P., Lee, D. S., Ellis, S. G., & Bhatt, D. L. (2006) · American Heart Journal · doi:10.1016/j.ahj.2005.08.011 · Cited by 413
Stone, G. W., Bertrand, M., Colombo, A., Dangas, G., Farkouh, M. E., Feit, F., Lansky, A. J., Lincoff, A. M., Mehran, R., Moses, J. W., et al. (2004) · American Heart Journal · doi:10.1016/j.ahj.2004.04.036 · Cited by 232
Self-citationParise, H., Maehara, A., Stone, G. W., Leon, M. B., & Mintz, G. S. (2011) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2010.09.030 · Cited by 189
Self-citationArmstrong, E. J., Feldman, D. N., Wang, T. Y., Kaltenbach, L. A., Yeo, K.-K., Wong, S. C., Spertus, J., Shaw, R. E., Minutello, R. M., Moussa, I., et al. (2012) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2011.10.013 · Cited by 181
Mehran, R., Brodie, B., Cox, D. A., Grines, C. L., Rutherford, B., Bhatt, D. L., Dangas, G., Feit, F., Ohman, E. M., Parise, H., et al. (2008) · American Heart Journal · doi:10.1016/j.ahj.2008.02.008 · Cited by 160
Self-citationHur, S., Kang, S., Kim, Y., Ahn, J., Park, D., Lee, S., Yun, S., Lee, C. W., Park, S., & Park, S. (2011) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.23279 · Cited by 55
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2018 ESC/EACTS guidelines on myocardial revascularization
Neumann, F.-J., Sousa-Uva, M., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehy394 · Cited by 7,167
Self-citation2018 ESC/EACTS Guidelines on myocardial revascularization
Neumann, F.-J., Sousa-Uva, M., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · EuroIntervention · doi:10.4244/eijy19m01_01 · Cited by 1,259
Self-citation2018 ESC/EACTS Guidelines on myocardial revascularization
Sousa-Uva, M., Neumann, F.-J., Ahlsson, A., Alfonso, F., Banning, A. P., Benedetto, U., Byrne, R. A., Collet, J.-P., Falk, V., Head, S. J., et al. (2019) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezy289 · Cited by 989
Self-citationRäber, L., Mintz, G. S., Koskinas, K. C., Johnson, T. W., Holm, N. R., Onuma, Y., Radu, M. D., Joner, M., Yu, B., Jia, H., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy285 · Cited by 770
Self-citationAli, Z. A., Maehara, A., Généreux, P., Shlofmitz, R. A., Fabbiocchi, F., Nazif, T. M., Guagliumi, G., Meraj, P. M., Alfonso, F., Samady, H., et al. (2016) · The Lancet · doi:10.1016/s0140-6736(16)31922-5 · Cited by 658
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Metadata
- Authors
- Witzenbichler, B., Maehara, A., Weisz, G., Neumann, F.-J., Rinaldi, M. J., Metzger, D. C., Henry, T. D., Cox, D. A., Duffy, P. L., Brodie, B. R., Stuckey, T. D., Mazzaferri, E. L., Xu, K., Parise, H., Mehran, R., Mintz, G. S., & Stone, G. W.
- Venue
- Circulation
- Published
- 2014-01-28
- Volume
- 129
- Issue
- 4
- Pages
- 463-470
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2015254392
- Cited by
- 408
- References
- 12
- FWCI
- 32.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Relationship Between Intravascular Ultrasound Guidance and Clinical Outcomes After Drug-Eluting Stents: The Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents (ADAPT-DES) Study. https://app.cochat.ai/papers/10.1161/circulationaha.113.003942
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- Witzenbichler, B., Maehara, A., Weisz, G., Neumann, F.-J., Rinaldi, M. J., Metzger, D. C., Henry, T. D., Cox, D. A., Duffy, P. L., Brodie, B. R., Stuckey, T. D., Mazzaferri, E. L., Xu, K., Parise, H., Mehran, R., Mintz, G. S., & Stone, G. W. (2014). Relationship Between Intravascular Ultrasound Guidance and Clinical Outcomes After Drug-Eluting Stents: The Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents (ADAPT-DES) Study. Circulation. https://doi.org/10.1161/circulationaha.113.003942
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