Xanthine Oxidase Inhibitors in Heart Failure: Where Do We Go From Here?
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Oxidation of tyrosine phosphatases by peroxynitrite results in the inhibition of their enzymatic activity and the aberrant propagation of phosphorylative signaling.
“Oxidation of tyrosine phosphatases results in the inhibition of their enzymatic activity and the aberrant propagation of phosphorylative signaling (926).”
From Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation (2019) · cites this paper as [926]
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References 24 · Cited by 39
- Authors
- Tamariz, L., & Hare, J. M.
- Affiliations
- University of Miami (US)
- Venue
- Circulation
- Published
- 2015-05-19
- Volume
- 131
- Issue
- 20
- Pages
- 1741-1744
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- PMC
- PMC4438774
- OpenAlex
- W2065947013
- Cited by
- 39
- References
- 24
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 5 · 2023: 1 · 2022: 3 · 2021: 5 · 2020: 7 · 2019: 2 · 2018: 4 · 2017: 3 · 2016: 3 · 2015: 2
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- U.S. Public Health Service (5UMHL113460)
- National Heart, Lung, and Blood Institute (R01HL110737, R01HL084275, UM1HL113460, R01HL107110)
- Topics
- Health Sciences › Medicine › Nephrology › Gout, Hyperuricemia, Uric Acid
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Biochemical and Molecular Research
- Keywords
- xanthine oxidase inhibitors, heart failure, uric acid, xanthine oxidase, urate-lowering therapy
- MeSH terms
- Allopurinol, Female, Heart Failure, Humans, Male, Xanthine Oxidase, Hyperuricemia
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