Sodium-glucose cotransporter-2 inhibitors in heart failure: racial differences and a potential for reducing disparities
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Black individuals have higher prevalence of type 2 diabetes, heart failure, chronic kidney disease, and premature coronary artery disease, along with worse cardiovascular outcomes.
“This gap is especially concerning given the higher prevalence of T2DM, heart failure, chronic kidney disease, and premature CAD among Black individuals, along with worse cardiovascular outcomes [14,15].”
From Unequal Access to Evidence-Based Cardiometabolic Therapies: Racial Disparities in SGLT2 Inhibitor and GLP-1 Receptor Agonist Use Among Patients With Type 2 Diabetes and Cardiovascular Disease (2026) · cites this paper as [14]
The main text (page unavailable) says Black patients have a high prevalence of heart failure, diabetes, and chronic kidney disease, and reports higher rates of death and hospitalization from heart failure. It does not specify type 2 diabetes or address premature coronary artery disease; it also does not explicitly compare diabetes or kidney-disease prevalence with other groups. (LLM, conf=0.86)
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References 5 · Cited by 22
- Authors
- Morris, A. A., Testani, J. M., & Butler, J.
- Affiliations
- Emory University (US)
- Yale University (US)
- University of Mississippi (US)
- Venue
- Circulation
- Published
- 2021-06-15
- Volume
- 143
- Issue
- 24
- Pages
- 2329-2331
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- PMC
- PMC8210466
- OpenAlex
- W3169938601
- Cited by
- 22
- References
- 5
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 3 · 2023: 6 · 2022: 5 · 2021: 1
- FWCI
- 2.51
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (UL1TR001863)
- National Heart, Lung, and Blood Institute (R03HL146874)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Keywords
- SGLT2 inhibitors, heart failure, racial disparities, ethnic differences, health disparities
- MeSH terms
- Race Factors, Sodium-Glucose Transporter 2 Inhibitors, Heart Failure, Hospitalization, Humans, Black People, Healthcare Disparities
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