The DOI matches its Crossref record; 81 of the 81 references it cites were found in a registry or an index.
Critical Limb Ischemia: Current Trends and Future Directions
Open accessAbstract
C ritical limb ischemia (CLI), which is at the end of the peripheral artery disease (PAD) spectrum, is associated with excessively high risk for cardiovascular events, including myocardial infarction, and death.[1][2][3] Mortality rates as high as 20% within 6 months from diagnosis and exceeding 50% at 5 years have been reported for CLI, 4-6 whereas 1-year mortality rates in nonrevascularizable, so-called no-option CLI patients range from 10% to 40%.7,8 The high mortality rates exceed those for every other form of occlusive cardiovascular disease, including symptomatic coronary artery disease (CAD), 9,10 and reflect the systemic atherosclerotic burden associated with CLI.Besides poor survival rates, prognosis with respect to limb preservation in CLI patients is poor, 11 particularly in no-option CLI patients, where 6-month major amputation rates have been reported to range from 10% to 40%.[6][7][8] Additionally, CLI is associated with poor quality of life 12 and high treatment costs, 13 especially when amputation is inevitable.13,14 With an estimated yearly incidence of 500 to 1000 new cases per million individuals in Western society, 7 which is ever increasing in concert with the increase in cardiovascular risk factors, 15-17 CLI poses a substantial burden on patients, healthcare providers, and resources.In the current review we will describe how management strategies in CLI have evolved over the past decades and discuss issues that could facilitate more rapid and evidencebased improvements in CLI management and care.Focus will be on factors that may have limited evidence-based management and on actions that could promote progress in this field, especially with respect to clinical research.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II)
Norgren, L., Hiatt, W. R., Dormandy, J. A., Nehler, M. R., Harris, K. A., & Fowkes, F. G. R. (2007) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2006.12.037 · Cited by 8,191
Recommended standards for reports dealing with lower extremity ischemia: Revised version
Rutherford, R. B., Baker, J. D., Ernst, C., Johnston, K. W., Porter, J. M., Ahn, S., & Jones, D. N. (1997) · Journal of Vascular Surgery · doi:10.1016/s0741-5214(97)70045-4 · Cited by 3,562
Peripheral Arterial Disease Detection, Awareness, and Treatment in Primary Care
Hirsch, A. T. (2001) · JAMA · doi:10.1001/jama.286.11.1317 · Cited by 2,835
Mortality over a Period of 10 Years in Patients with Peripheral Arterial Disease
Criqui, M. H., Langer, R. D., Fronek, A., Feigelson, H. S., Klauber, M. R., McCann, T. J., & Browner, D. (1992) · New England Journal of Medicine · doi:10.1056/nejm199202063260605 · Cited by 2,579
(2005) · The Lancet · doi:10.1016/s0140-6736(05)67704-5 · Cited by 1,941
Mills, J. L., Conte, M. S., Armstrong, D. G., Pomposelli, F. B., Schanzer, A., Sidawy, A. N., & Andros, G. (2014) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2013.08.003 · Cited by 1,718
Self-citationDormandy, J., & Rutherford, R. B. (2000) · PubMed · Cited by 1,635
One-year cardiovascular event rates in outpatients with atherothrombosis
Steg, P. G., Bhatt, D. L., Wilson, P. W. F., D’Agostino, R., Ohman, E. M., Röther, J., Liau, C.-S., Hirsch, A. T., Mas, J.-L., Ikeda, Y., et al. (2007) · JAMA · doi:10.1001/jama.297.11.1197 · Cited by 1,382
Phillips, L. S., Branch, W. T., Cook, C. B., Doyle, J. P., El-Kebbi, I. M., Gallina, D. L., Miller, C. D., Ziemer, D. C., & Barnes, C. S. (2001) · Annals of Internal Medicine · doi:10.7326/0003-4819-135-9-200111060-00012 · Cited by 1,370
Suggested standards for reports dealing with lower extremity ischemia
Rutherford, R. B., Flanigan, D. P., Gupta, S. K., Johnston, K. W., Karmody, A., Whittemore, A. D., Baker, J. D., Ernst, C. B., Jamieson, C., & Mehta, S. (1986) · Journal of Vascular Surgery · doi:10.1016/0741-5214(86)90326-5 · Cited by 1,081
Cited by
Aboyans, V., Ricco, J.-B., Bartelink, M.-L. E. L., Björck, M., Brodmann, M., Cohnert, T., Collet, J.-P., Czerny, M., De Carlo, M., Debus, S., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehx095 · Cited by 3,293
Aboyans, V., Ricco, J.-B., Bartelink, M.-L. E. L., Björck, M., Brodmann, M., Cohnert, T., Collet, J.-P., Czerny, M., De Carlo, M., Debus, S., et al. (2018) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2017.07.018 · Cited by 963
Epidemiology of Peripheral Arterial Disease and Critical Limb Ischemia
Dua, A., & Lee, C. J. (2016) · Techniques in Vascular and Interventional Radiology · doi:10.1053/j.tvir.2016.04.001 · Cited by 266
Metadata
- Authors
- Teraa, M., Conte, M. S., Moll, F. L., & Verhaar, M. C.
- Venue
- Journal of the American Heart Association
- Published
- 2016-02-23
- Volume
- 5
- Issue
- 2
- ISSN
- 2047-9980 (ISSN-L)
- OpenAlex
- W2279728460
- Cited by
- 256
- References
- 81
- FWCI
- 29.21
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Critical Limb Ischemia: Current Trends and Future Directions. https://app.cochat.ai/papers/10.1161/jaha.115.002938
- The paper
- Teraa, M., Conte, M. S., Moll, F. L., & Verhaar, M. C. (2016). Critical Limb Ischemia: Current Trends and Future Directions. Journal of the American Heart Association. https://doi.org/10.1161/jaha.115.002938
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
