Progression of White Matter Hyperintensities and Incidence of New Lacunes Over a 3-Year Period

Gouw, Alida A.; van der Flier, Wiesje M.; Fazekas, Franz; van Straaten, Elisabeth C.W.; Pantoni, Leonardo; Poggesi, Anna; Inzitari, Domenico; Erkinjuntti, Timo; Wahlund, Lars O.; Waldemar, Gunhild; Schmidt, Reinhold; Scheltens, Philip; Barkhof, Frederik

doi:10.1161/strokeaha.107.498535

Progression of White Matter Hyperintensities and Incidence of New Lacunes Over a 3-Year Period

Background and Purpose— We studied the natural course of white matter hyperintensities (WMH) and lacunes, the main MRI representatives of small vessel disease, over time and evaluated possible predictors for their development. Methods— Baseline and repeat MRI (3-year follow-up) were collected wit…