The DOI matches its Crossref record; 68 of the 68 references it cites were found in a registry or an index.
Magnesium Sulfate for the Treatment of Eclampsia: A Brief Review
Open accessAbstract
Background and Purpose—Magnesium sulfate is used extensively for prevention of eclamptic seizures. Empirical and clinical evidence supports the effectiveness of magnesium sulfate; however, questions remain as to its safety and mechanism. This review summarizes current evidence supporting the possible mechanisms of action and several controversies for magnesium sulfate treatment. Summary of Review—Several mechanisms are presented, including the effects of magnesium sulfate on peripheral and cerebral vasodilation, blood-brain barrier protection, and as an anticonvulsant. Conclusions—Though the specific mechanisms of action remain unclear, the effect of magnesium sulfate in the prevention of eclampsia is likely multi-factorial. Magnesium sulfate may act as a vasodilator, with actions in the peripheral vasculature or the cerebrovasculature, to decrease peripheral vascular resistance or relieve vasoconstriction. Additionally, magnesium sulfate may also protect the blood-brain barrier and limit cerebral edema formation, or it may act through a central anticonvulsant action.
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Cites
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Preeclampsia: an endothelial cell disorder
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Cited by
Magnesium in man: implications for health and disease
de Baaij, J. H. F., Hoenderop, J. G. J., & Bindels, R. J. M. (2015) · Physiological Reviews · doi:10.1152/physrev.00012.2014 · Cited by 1,726
Magnesium in Prevention and Therapy
Gröber, U., Schmidt, J., & Kisters, K. (2015) · Nutrients · doi:10.3390/nu7095388 · Cited by 1,061
Common variants associated with general and MMR vaccine–related febrile seizures
Feenstra, B., Pasternak, B., Geller, F., Carstensen, L., Wang, T., Huang, F., Eitson, J. L., Hollegaard, M. V., Svanström, H., Vestergaard, M., et al. (2014) · Nature Genetics · doi:10.1038/ng.3129 · Cited by 152
Hupp, S., Ribes, S., Seele, J., Bischoff, C., Förtsch, C., Maier, E., Benz, R., Mitchell, T. J., Nau, R., & Iliev, A. I. (2017) · British Journal of Pharmacology · doi:10.1111/bph.14027 · Cited by 12
Metadata
- Authors
- Euser, A. G., & Cipolla, M. J.
- Venue
- Stroke
- Published
- 2009-04
- Volume
- 40
- Issue
- 4
- Pages
- 1169-1175
- ISSN
- 0039-2499 (ISSN-L)
- 1524-4628
- OpenAlex
- W1975114737
- Cited by
- 310
- References
- 68
- FWCI
- 17.52
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
