The DOI matches its Crossref record.
Caveolin Scaffolding Domain LTI-03 Modulates Both Inflammatory and Fibrotic Responses in Aged Mice After Bleomycin Challenge
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In the citing paper
“LTI-03 has been shown to exert strong antifibrotic and epithelial supportive effects in experimental animal models of lung fibrosis15–17, in human IPF precision cut lung slices18, and in human IPF alveolar organoids19.”
From Inhaled LTI-03 for idiopathic pulmonary fibrosis: a randomized dose escalation study (2026) · cites this paper as [17]
In the citing paper
“This is consistent with results from aged male mice challenged with bleomycin, in which BALF levels of IL-11 were reduced with LTI-03 treatment17.”
From Inhaled LTI-03 for idiopathic pulmonary fibrosis: a randomized dose escalation study (2026) · cites this paper as [17]
In the citing paper
“LTI-03 consistently reduced collagen expression and deposition in animal models and in vitro17,20.”
From Inhaled LTI-03 for idiopathic pulmonary fibrosis: a randomized dose escalation study (2026) · cites this paper as [17]
Citations
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Inhaled LTI-03 for idiopathic pulmonary fibrosis: a randomized dose escalation study
Molyneaux, P. L., Hirani, N. A., Chia, C. C. K., Kulkarni, T., Zaman, T., Kaner, R. J., Coelho, A. L., Jannini-Sa, Y. A. P., Windsor, B., Kruger, S., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-75291-3 · Cited by 1
Self-citation
Metadata
- Authors
- Mackenzie, B., Maier, E., Creyns, B., Coelho, A. L., Windsor, B., & Hogaboam, C. M.
- Affiliations
- Lung Therapeutics, Inc, Austin, TX, United States
- The University of Texas at Austin (US)
- Cedars-Sinai Medical Center (US)
- Venue
- A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY
- Publisher
- American Thoracic Society
- Published
- 2022-05
- Pages
- A2307-A2307
- ISSN
- 1073-449X (ISSN-L)
- OpenAlex
- W4225275289
- Cited by
- 0
- References
- 0
- Type
- conference abstract
- Language
- en
- Open access
- closed
- Locations
- American Journal of Respiratory and Critical Care Medicine (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Caveolin-1 and cellular processes
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Effects of Radiation Exposure
- Keywords
- caveolin scaffolding domain, caveolin-1, pulmonary fibrosis, bleomycin-induced lung injury, inflammation, aging, antifibrotic therapy
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Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Caveolin Scaffolding Domain LTI-03 Modulates Both Inflammatory and Fibrotic Responses in Aged Mice After Bleomycin Challenge. https://app.cochat.ai/papers/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2307
- The paper
- Mackenzie, B., Maier, E., Creyns, B., Coelho, A. L., Windsor, B., & Hogaboam, C. M. (2022). Caveolin Scaffolding Domain LTI-03 Modulates Both Inflammatory and Fibrotic Responses in Aged Mice After Bleomycin Challenge. A107. MECHANISMS OF FIBROSIS/FIBROBLAST BIOLOGY. https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a2307