The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Comparison of three methods of gradual withdrawal from ventilatory support during weaning from mechanical ventilation.
Abstract
Several modalities of ventilatory support have been proposed to gradually withdraw patients from mechanical ventilation, but their respective effects on the outcome of weaning from mechanical ventilation are not known. We conducted a randomized trial in three intensive care units in mechanically ventilated patients who met standard weaning criteria. Those who could not sustain 2 h of spontaneous breathing were randomly assigned to be weaned with T-piece trials, with synchronized intermittent mandatory ventilation (SIMV), or with pressure support ventilation (PSV). Specific criteria for performing tracheal extubation were defined for each modality. The number of patients who could not be separated from the ventilator at 21 d (i.e., who failed to wean) was compared between the groups. Patients in whom tracheal intubation was required in a 48-h period following extubation were also classified as failures. Among 456 mechanically ventilated patients who met weaning criteria, 109 entered into the study (35 with T piece, 43 with SIMV, and 31 with PSV). The three groups were comparable in terms of etiology of disease or characteristics at entry in the study. When all causes for weaning failure were considered, a lower number of failures was found with PSV than with the other two modes, with the difference just reaching the level of significance (23% for PSV, 43% for T piece, 42% for SIMV; p = 0.05). After excluding patients whose weaning was terminated for complications unrelated to the weaning process, the difference became highly significant (8% for PSV versus 33% and 39%, p < 0.025).(ABSTRACT TRUNCATED AT 250 WORDS)
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Peto, R., Pike, M. C., Armitage, P., Breslow, N. E., Cox, D. R., Howard, S. V., Mantel, N., McPherson, K., Peto, J., & Smith, P. G. (1977) · British Journal of Cancer · doi:10.1038/bjc.1977.1 · Cited by 8,285
Evaluation of survival data and two new rank order statistics arising in its consideration.
Mantel, N. (1966) · PubMed · Cited by 7,519
Yang, K. L., & Tobin, M. J. (1991) · New England Journal of Medicine · doi:10.1056/nejm199105233242101 · Cited by 1,378
Brochard, L., Harf, A., Lorino, H., & Lemaire, F. (1989) · American Review of Respiratory Disease · doi:10.1164/ajrccm/139.2.513 · Cited by 630
Self-citationRespiratory muscle strength and maximal voluntary ventilation in undernourished patients.
ARORA, N. S., & Rochester, D. F. (1982) · PubMed · doi:10.1164/arrd.1982.126.1.5 · Cited by 612
Impact of PEEP on lung mechanics and work of breathing in severe airflow obstruction
Smith, T. C., & Marini, J. J. (1988) · Journal of Applied Physiology · doi:10.1152/jappl.1988.65.4.1488 · Cited by 511
Respiratory Function during Pressure Support Ventilation
MacIntyre, N. R. (1986) · Chest · doi:10.1378/chest.89.5.677 · Cited by 415
Brochard, L., Rua, F., Lorino, H., Lemaire, F., & Harf, A. (1991) · Anesthesiology · doi:10.1097/00000542-199111000-00004 · Cited by 348
Self-citation(1987) · Journal of Critical Care · doi:10.1016/0883-9441(87)90022-0 · Cited by 335
Marini, J. J., Smith, T. C., & Lamb, V. J. (1988) · American Review of Respiratory Disease · doi:10.1164/ajrccm/138.5.1169 · Cited by 231
Cited by
Vestbo, J., Hurd, S. S., Agustí, A. G., Jones, P. W., Vogelmeier, C., Anzueto, A., Barnes, P. J., Fabbri, L. M., Martinez, F. J., Nishimura, M., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201204-0596pp · Cited by 15,983
Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock
Dellinger, R. P., Levy, M. M., Rhodes, A., Annane, D., Gerlach, H., Opal, S. M., Sevransky, J. E., Sprung, C. L., Douglas, I. S., Jaeschke, R., et al. (2013) · Critical Care Medicine · doi:10.1097/ccm.0b013e31827e83af · Cited by 9,694
Rabe, K. F., Hurd, S., Anzueto, A., Barnes, P. J., Buist, S. A., Calverley, P., Fukuchi, Y., Jenkins, C., Rodriguez-Roisin, R., van Weel, C., et al. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200703-456so · Cited by 4,925
Antonelli, M., Conti, G., Rocco, M., Bufi, M., De Blasi, R. A., Vivino, G., Gasparetto, A., & Meduri, G. U. (1998) · New England Journal of Medicine · doi:10.1056/nejm199808133390703 · Cited by 1,014
Self-citationThe Use of Continuous IV Sedation Is Associated With Prolongation of Mechanical Ventilation
Kollef, M. H., Levy, N. T., Ahrens, T. S., Schaiff, R., Prentice, D., & Sherman, G. (1998) · Chest · doi:10.1378/chest.114.2.541 · Cited by 916
Metadata
- Authors
- Brochard, L., Rauss, A., Benito, S., Conti, G., Mancebo, J., Rekik, N., Gasparetto, A., & Lemaire, F.
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 1994-10
- Volume
- 150
- Issue
- 4
- Pages
- 896-903
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2157202254
- Cited by
- 1,122
- References
- 12
- FWCI
- 23.88
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Comparison of three methods of gradual withdrawal from ventilatory support during weaning from mechanical ventilation. https://app.cochat.ai/papers/10.1164/ajrccm.150.4.7921460
- The paper
- Brochard, L., Rauss, A., Benito, S., Conti, G., Mancebo, J., Rekik, N., Gasparetto, A., & Lemaire, F. (1994). Comparison of three methods of gradual withdrawal from ventilatory support during weaning from mechanical ventilation. American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/ajrccm.150.4.7921460
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
