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Cited by 265Chronic Obstructive Pulmonary Disease (COPD) ResearchHealth Systems, Economic Evaluations, Quality of LifeAsthma and respiratory diseases

The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.

Comparison of Discriminative Properties among Disease-specific Questionnaires for Measuring Health-related Quality of Life in Patients with Chronic Obstructive Pulmonary Disease

HAJIRO, TAKASHI, NISHIMURA, KOICHI, TSUKINO, MITSUHIRO, IKEDA, AKIHIKO, KOYAMA, HIROSHI, IZUMI, TAKATERU·1998·American Journal of Respiratory and Critical Care Medicine
DOI 10.1164/ajrccm.157.3.9703055
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Abstract

Three disease-specific, health-related quality of life (HRQL) questionnaires have been introduced to assess patients with chronic obstructive pulmonary disease (COPD): the St. George's Respiratory Questionnaire (SGRQ), the Breathing Problems Questionnaire (BPQ), and the Chronic Respiratory Disease Questionnaire (CRQ). The purpose of the present study was to make comparisons between the SGRQ, the BPQ, and the CRQ in their discriminative properties, and to clarify the characteristics of each questionnaire. One hundred forty-three patients with mild to severe COPD completed pulmonary function tests, progressive cycle ergometer testing for exercise capacity, assessment of dyspnea, anxiety, and depression, and assessment of HRQL. The frequency distributions of the questionnaire scores showed that the SGRQ and the CRQ were normally distributed and that the BPQ was skewed toward low scores. Relationships between all dimensions of the three questionnaires were significant (correlation coefficients [Rs] = 0.74 to 0.86). The three questionnaires had significant but weak correlations (Rs = -0.24 to -0.36) with some physiologic variables (VC, FEV1, and DL(CO)/VA) and mild to moderate correlations with exercise capacity and assessment of dyspnea, anxiety, and depression. Stepwise multiple regression analyses revealed that the Baseline Dyspnea Index (BDI) score, anxiety by the Hospital Anxiety Depression Scale (HAD), and maximal oxygen uptake (VO2max) accounted for 61% of the variance in the SGRQ and that the BDI and anxiety of the HAD accounted for 53 and 49% of the variance in the BPQ and the CRQ, respectively. Dyspnea and psychologic status impacted the HRQL in patients with COPD. Although no substantial differences between the SGRQ, the BPQ, and the CRQ were evident in the correlations with physiologic parameters and the influential factors, the BPQ was found to be less discriminatory than the SGRQ and the CRQ in evaluating HRQL cross-sectionally.

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  1. Medical Section of the American Lung Association, 1994, Standardization of spirometry: 1994 update., Am. Rev. Respir. Dis., 152, 1107

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Metadata

Authors
HAJIRO, T., NISHIMURA, K., TSUKINO, M., IKEDA, A., KOYAMA, H., & IZUMI, T.
Affiliations
Kyoto University (JP)
ORCID
Venue
American Journal of Respiratory and Critical Care Medicine
Publisher
Oxford University Press (OUP)
Published
1998-03-01
Volume
157
Issue
3
Pages
785-790
ISSN
  • 1073-449X (ISSN-L)
  • 1535-4970
DOI
10.1164/ajrccm.157.3.9703055
OpenAlex
W2071805440
Cited by
265
References
21
Citations by year
2026: 3 · 2025: 3 · 2024: 2 · 2023: 8 · 2021: 8 · 2020: 7 · 2019: 6 · 2018: 6 · 2017: 11 · 2016: 8 · 2015: 8 · 2014: 13 · 2013: 14 · 2012: 14
FWCI
7.36
Type
journal article
Language
en
Open access
closed
Licence
academic.oup.com/pages/standard-publication-reuse-rights (vor)
Locations
  • American Journal of Respiratory and Critical Care Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
  • Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
Keywords
chronic obstructive pulmonary disease, health-related quality of life, disease-specific questionnaire, St George's Respiratory Questionnaire, Chronic Respiratory Questionnaire, dyspnea, anxiety, depression, exercise capacity, VO2max, lung function
MeSH terms
Aged, Aged, 80 and over, Anxiety, Cross-Sectional Studies, Depression, Dyspnea, Evaluation Studies as Topic, Exercise Test, Forced Expiratory Volume, Health Status, Humans, Lung Diseases, Obstructive, Middle Aged, Oxygen Consumption, Pulmonary Diffusing Capacity, Quality of Life, Surveys and Questionnaires, Regression Analysis, Respiration, Respiratory Function Tests, Vital Capacity, Discriminant Analysis, Exercise Tolerance

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