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Cited by 34Tuberculosis Research and EpidemiologyMycobacterium research and diagnosisInfectious Diseases and Tuberculosis

The DOI matches its Crossref record.

Minimal Inhibitory Concentrations of Rifabutin, Ciprofloxacin, and Ofloxacin against Mycobacterium tuberculosis Isolated before Treatment of Patients in Taiwan

Chen, Chung-Hua, Shih, Jen-Fu, Lindholm-Levy, Pamela J., Heifets, Leonid B.·1989·American Review of Respiratory Disease
DOI 10.1164/ajrccm/140.4.987
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Abstract

Minimal inhibitory concentrations (MICs) of rifabutin, ciprofloxacin, and ofloxacin were determined for "wild" Mycobacterium tuberculosis strains, susceptible to all antituberculosis drugs in the conventional test, isolated from newly diagnosed Taiwanese patients who had never had prior treatment for tuberculosis. These MICs were within the limits previously reported for strains isolated in the United States. The range of MICs of rifabutin for Taiwanese strains was 0.015 to 0.125 micrograms/ml; ciprofloxacin, 0.25 to 2.0 micrograms/ml; ofloxacin, 0.5 to 2.0 micrograms/ml. On the basis of an evaluation of the highest broth-determined MICs found in this and in a previous study, we suggest that the following MICs, when determined in 7H12 broth radiometrically, should be used as breakpoints to classify the strain as "susceptible": for rifabutin, 0.125 micrograms/ml or less; for ofloxacin and ciprofloxacin, 2.0 micrograms/ml or less.

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Research works printed but not linked: 14

  1. O'Brien RT, 1985, Am Rev Respir Dis, 131, 309
  2. 1988, Rev Respir Dis, 137, 719, 10.1164/ajrccm/137.3.719 · DOI
  3. 1985, Chemother, 16, 575
  4. 1985, Microbiol, 4, 345
  5. 1985, Agents Chemother, 27, II-5
  6. 1981, Am Rev Respir Dis, 123, 402
  7. 1985, J Clin Microbiol, 21, 941, 10.1128/JCM.21.6.941-946.1985 · DOI
  8. 1987, Clin Microbiol, 6, 584
  9. 10.1128/AAC.26.1.94 · DOI
  10. 10.1128/AAC.29.3.386 · DOI
  11. 1987, Kekkaku, 62, 287
  12. 10.1093/jac/21.4.501 · DOI
  13. 10.1016/0769-2609(88)90008-7 · DOI
  14. 1988, Respir Dis, 137, 1217, 10.1164/ajrccm/137.5.1217 · DOI

Cited by

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Metadata

Authors
Chen, C.-H., Shih, J.-F., Lindholm-Levy, P. J., & Heifets, L. B.
Affiliations
Taipei Veterans General Hospital (TW)
Venue
American Review of Respiratory Disease
Publisher
Oxford University Press (OUP)
Published
1989-10-01
Volume
140
Issue
4
Pages
987-989
ISSN
0003-0805 (ISSN-L)
DOI
10.1164/ajrccm/140.4.987
OpenAlex
W2052855222
Cited by
34
References
0
Citations by year
2026: 1 · 2024: 1 · 2023: 1 · 2017: 1 · 2015: 1 · 2014: 1
FWCI
1.12
Type
journal article
Language
en
Open access
closed
Licence
academic.oup.com/pages/standard-publication-reuse-rights (vor)
Locations
  • American Review of Respiratory Disease (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
  • Health Sciences › Medicine › Epidemiology › Mycobacterium research and diagnosis
  • Health Sciences › Medicine › Infectious Diseases › Infectious Diseases and Tuberculosis
Keywords
Mycobacterium tuberculosis, rifabutin, ciprofloxacin, ofloxacin, minimum inhibitory concentration, fluoroquinolones, rifamycin derivatives, Taiwan
MeSH terms
Antitubercular Agents, Ciprofloxacin, Culture Media, Dose-Response Relationship, Drug, Drug Resistance, Microbial, Humans, Mycobacterium tuberculosis, Rifamycins, Taiwan, Tuberculosis, Pulmonary, United States, Ofloxacin, Rifabutin

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CoChat. (2026). Citation check: Minimal Inhibitory Concentrations of Rifabutin, Ciprofloxacin, and Ofloxacin against Mycobacterium tuberculosis Isolated before Treatment of Patients in Taiwan. https://app.cochat.ai/papers/10.1164/ajrccm/140.4.987
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Chen, C.-H., Shih, J.-F., Lindholm-Levy, P. J., & Heifets, L. B. (1989). Minimal Inhibitory Concentrations of Rifabutin, Ciprofloxacin, and Ofloxacin against Mycobacterium tuberculosis Isolated before Treatment of Patients in Taiwan. American Review of Respiratory Disease. https://doi.org/10.1164/ajrccm/140.4.987