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Cited by 354Obstructive Sleep Apnea ResearchSleep and related disordersBlood Pressure and Hypertension Studies

The DOI matches its Crossref record; 57 of the 57 references it cites were found in a registry or an index.

Twenty-four-hour ambulatory blood pressure in children with sleep-disordered breathing

Amin, Raouf S., Carroll, John L., Jeffries, Jenny L., Grone, Charles, Bean, Judy A., Chini, Barbara, Bokulic, Ronald, Daniels, Stephen R.·2004·American Journal of Respiratory and Critical Care Medicine
DOI 10.1164/rccm.200309-1305oc
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Abstract

Obstructive sleep apnea causes intermittent elevation of systemic blood pressure (BP) during sleep. To determine whether obstructive apnea in children has a tonic effect on diurnal BP, 24-hour ambulatory blood pressure was obtained from 60 children with mean age of 10.8 +/- 3.5 years. Thirty-nine children had obstructive apnea and 21 had primary snoring. Children with obstructive apnea had significantly greater mean BP variability during wakefulness and sleep, a higher night-to-day systolic BP, and a smaller nocturnal dipping of mean BP. Variability of mean arterial pressure during wakefulness was predicted by the desaturation, body mass, and arousal indices, whereas variability during sleep was predicted by apnea-hypopnea and body mass indices. Nocturnal BP dipping was predicted by the desaturation index. There were no significant differences in systolic, diastolic, or mean arterial BP during sleep between the groups. Diastolic BP during wakefulness was significantly different between the groups and correlated negatively with apnea-hypopnea index. We conclude that obstructive apnea in children is associated with 24-hour BP dysregulation and that, independent of obesity, the frequency of obstructive apnea, oxygen desaturation, and arousal contributes to abnormal BP control.

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Crossref · 10.1164/rccm.200309-1305oc

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Citations

Cites

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Research works printed but not linked: 54

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Metadata

Authors
Amin, R. S., Carroll, J. L., Jeffries, J. L., Grone, C., Bean, J. A., Chini, B., Bokulic, R., & Daniels, S. R.
Affiliations
Cincinnati Children's Hospital Medical Center (US)
ORCID
Venue
American Journal of Respiratory and Critical Care Medicine
Publisher
Oxford University Press (OUP)
Published
2004-04
Volume
169
Issue
8
Pages
950-956
ISSN
  • 1073-449X (ISSN-L)
  • 1535-4970
DOI
10.1164/rccm.200309-1305oc
OpenAlex
W2106542853
Cited by
354
References
57
Citations by year
2026: 8 · 2025: 6 · 2024: 9 · 2023: 11 · 2022: 7 · 2021: 10 · 2020: 14 · 2019: 8 · 2018: 15 · 2017: 12 · 2016: 21 · 2015: 17 · 2014: 16 · 2013: 18 · 2012: 23
FWCI
15.21
Type
journal article
Language
en
Open access
closed
Licence
academic.oup.com/pages/standard-publication-reuse-rights (vor)
Locations
  • American Journal of Respiratory and Critical Care Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
Keywords
obstructive sleep apnea, pediatric sleep-disordered breathing, ambulatory blood pressure, nocturnal blood pressure dipping, blood pressure variability, oxygen desaturation, arousal index, apnea-hypopnea index, body mass index, primary snoring, diastolic blood pressure
MeSH terms
Adolescent, Arousal, Blood Gas Analysis, Blood Pressure, Child, Child, Preschool, Circadian Rhythm, Female, Humans, Male, Oxyhemoglobins, Severity of Illness Index, Sleep, Sleep Apnea Syndromes, Body Mass Index, Polysomnography, Blood Pressure Monitoring, Ambulatory

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