The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Seeking Worldwide Professional Consensus on the Principles of End-of-Life Care for the Critically Ill. The Consensus for Worldwide End-of-Life Practice for Patients in Intensive Care Units (WELPICUS) Study
Abstract
Great differences in end-of-life practices in treating the critically ill around the world warrant agreement regarding the major ethical principles. This analysis determines the extent of worldwide consensus for end-of-life practices, delineates where there is and is not consensus, and analyzes reasons for lack of consensus. Critical care societies worldwide were invited to participate. Country coordinators were identified and draft statements were developed for major end-of-life issues and translated into six languages. Multidisciplinary responses using a web-based survey assessed agreement or disagreement with definitions and statements linked to anonymous demographic information. Consensus was prospectively defined as >80% agreement. Definitions and statements not obtaining consensus were revised based on comments of respondents, and then translated and redistributed. Of the initial 1,283 responses from 32 countries, consensus was found for 66 (81%) of the 81 definitions and statements; 26 (32%) had >90% agreement. With 83 additional responses to the original questionnaire (1,366 total) and 604 responses to the revised statements, consensus could be obtained for another 11 of the 15 statements. Consensus was obtained for informed consent, withholding and withdrawing life-sustaining treatment, legal requirements, intensive care unit therapies, cardiopulmonary resuscitation, shared decision making, medical and nursing consensus, brain death, and palliative care. Consensus wa…
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Structured, complex, multifaceted interventions in the context of advance care planning and shared decision making may effectively prevent disproportionate/unwanted end-of-life care and accordingly reduce use of healthcare resources. 4,7,44,72,355,398”
From European Resuscitation Council Guidelines 2021: Ethics of resuscitation and end of life decisions (2021) · cites this paper as [7]
In the citing paper
“Data from eight RCTs included in three systematic reviews indicated that communication interventions aiding the completion of advance directives had no significant effect on patient/family satisfaction with end-of-life care. 4,7,8”
From European Resuscitation Council Guidelines 2021: Ethics of resuscitation and end of life decisions (2021) · cites this paper as [7]
In the citing paper
“Evidence from 13 RCTs and from 8 nonrandomised studies included in 3 systematic reviews suggests associations of communication interventions with an increased frequency of DNACPR orders. 4,7,8,10”
From European Resuscitation Council Guidelines 2021: Ethics of resuscitation and end of life decisions (2021) · cites this paper as [7]
In the citing paper
“Despite the limitations of the currently available, substantial but still heterogenous, body of evidence, the presence of either positive or neutral RCTs on structured communication tools aimed at facilitating the completion of advance care directives and plans suggests a class effect and increased likelihood of benefit compared with usual care. 4,7”
From European Resuscitation Council Guidelines 2021: Ethics of resuscitation and end of life decisions (2021) · cites this paper as [7]
In the citing paper
“Accordingly, the certainty of existing evidence has been judged most frequently as low to very low by authors of systematic reviews. 7 10,28,38,39,43,44,72”
From European Resuscitation Council Guidelines 2021: Ethics of resuscitation and end of life decisions (2021) · cites this paper as [7]
Citations
Cites
Early Palliative Care for Patients with Metastatic Non–Small-Cell Lung Cancer
Temel, J. S., Greer, J. A., Muzikansky, A., Gallagher, E. R., Admane, S., Jackson, V. A., Dahlin, C. M., Blinderman, C. D., Jacobsen, J., Pirl, W. F., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1000678 · Cited by 7,482
Assessing patients' capacities to consent to treatment
Appelbaum, P. S., & Grisso, T. (1988) · New England Journal of Medicine · doi:10.1056/nejm198812223192504 · Cited by 1,399
Use of intensive care at the end of life in the United States: An epidemiologic study*
Angus, D. C., Barnato, A. E., Linde‐Zwirble, W. T., Weissfeld, L. A., Watson, R. S., Rickert, T., & Rubenfeld, G. D. (2004) · Critical Care Medicine · doi:10.1097/01.ccm.0000114816.62331.08 · Cited by 1,157
Truog, R. D., Campbell, M., Curtis, J. R., Haas, C. E., Luce, J. M., Rubenfeld, G. D., Rushton, C. H., & Kaufman, D. C. (2008) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181659096 · Cited by 1,100
Self-citationEnd-of-Life Practices in European Intensive Care Units
Sprung, C. L., Cohen, S. L., Sjökvist, P., Baras, M., Bülow, H., Hovilehto, S., Ledoux, D., Lippert, A. M., Maia, P., Phelan, D. M. J., et al. (2003) · JAMA · doi:10.1001/jama.290.6.790 · Cited by 1,064
Self-citationIncreasing Incidence of Withholding and Withdrawal of Life Support From the Critically Ill
Prendergast, T. J., & Luce, J. M. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.155.1.9001282 · Cited by 726
Current Research Findings on End-of-Life Decision Making Among Racially or Ethnically Diverse Groups
Kwak, J., & Haley, W. E. (2005) · The Gerontologist · doi:10.1093/geront/45.5.634 · Cited by 615
The Delphi method: Substance, context, a critique and an annotated bibliography
Pill, J. (1971) · Socio-Economic Planning Sciences · doi:10.1016/0038-0121(71)90041-3 · Cited by 579
Prevalence and Factors of Intensive Care Unit Conflicts: The Conflicus Study
Azoulay, É., Timsit, J., Sprung, C. L., Soares, M., Rusínová, K., Lafabrie, A., Abizanda, R., Svantesson, M., Rubulotta, F. M., Ricou, B., et al. (2009) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200810-1614oc · Cited by 553
Self-citationChallenges in end-of-life care in the ICU
Carlet, J. M., THIJS, L. G., Antonelli, M. M., Cassell, J., Cox, P. N., Hill, N. S., Hinds, C., Pimentel, J. M., Reinhart, K., & Thompson, B. (2004) · Intensive Care Medicine · doi:10.1007/s00134-004-2241-5 · Cited by 548
Self-citation
Research works printed but not linked: 2
- Sprung, 1989, Informed consent in theory and practice: legal and medical perspectives on the informed consent doctrine and a proposed reconceptualization, Crit Care Med, 17, 1346, 10.1097/00003246-198912000-00022 · DOI
- Yousuf, 2007, Using experts’ opinions through Delphi technique, Pract Assess Res Eval, 12, 4
Cited by
Sorted by citations
Surviving Sepsis Campaign: International guidelines for management of sepsis and septic shock: 2016.
Rhodes, A., Evans, L. E., Alhazzani, W., Levy, M. M., Antonelli, M., Ferrer, R., Kumar, A., Sevransky, J. E., Sprung, C. L., Nunnally, M. E., et al. (2017) · Intensive Care Medicine · doi:10.1007/s00134-017-4683-6 · Cited by 6,621
Self-citationSurviving Sepsis Campaign: International guidelines for management of sepsis and septic shock: 2016.
Rhodes, A., Evans, L. E., Alhazzani, W., Levy, M. M., Antonelli, M., Ferrer, R., Kumar, A., Sevransky, J. E., Sprung, C. L., Nunnally, M. E., et al. (2017) · Critical Care Medicine · doi:10.1097/ccm.0000000000002255 · Cited by 3,652
Self-citationJünger, S., Payne, S. A., Brine, J., Radbruch, L., & Brearley, S. G. (2017) · Palliative Medicine · doi:10.1177/0269216317690685 · Cited by 2,210
Determination of Brain Death/Death by Neurologic Criteria
Greer, D. M., Shemie, S. D., Lewis, A. K., Torrance, S., Varelas, P. N., Goldenberg, F. D., Bernat, J. L., Souter, M. J., Topçuoğlu, M. A., Alexandrov, A. W., et al. (2020) · JAMA · doi:10.1001/jama.2020.11586 · Cited by 653
Mark, N. M., Rayner, S. G., Lee, N. J., & Curtis, J. R. (2015) · Intensive Care Medicine · doi:10.1007/s00134-015-3810-5 · Cited by 339
Self-citationChanges in End-of-Life Practices in European Intensive Care Units From 1999 to 2016
Sprung, C. L., Ricou, B., Hartog, C. S., Maia, P., Mentzelopoulos, S. D., Weiß, M., Levin, P. D., Galarza, L., de la Guardia, V., Schefold, J. C., et al. (2019) · JAMA · doi:10.1001/jama.2019.14608 · Cited by 259
Self-citationEuropean Resuscitation Council Guidelines 2021: Ethics of resuscitation and end of life decisions
Mentzelopoulos, S. D., Couper, K., Voorde, P. V. D., Druwé, P., Blom, M., Perkins, G. D., Lulic, I., Djakow, J., Raffay, V., Lilja, G., et al. (2021) · Resuscitation · doi:10.1016/j.resuscitation.2021.02.017 · Cited by 246
Withholding and Withdrawal of Life-Sustaining Treatments in Intensive Care Units in Asia
Phua, J., Joynt, G. M., Nishimura, M., Deng, Y., Myatra, S. N., Chan, Y. H., Bình, N. G., Tan, C. C., Faruq, M. O., Arabi, Y. M., et al. (2015) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2014.7386 · Cited by 229
Self-citationMichalsen, A., Long, A. C., Ganz, F. D., White, D. B., Jensen, H. I., Metaxa, V., Hartog, C. S., Latour, J. M., Truog, R. D., Kesecioğlu, J., et al. (2019) · Critical Care Medicine · doi:10.1097/ccm.0000000000003870 · Cited by 196
Self-citationRussell, J. A., Epstein, L. G., Greer, D. M., Kirschen, M. P., Rubin, M. A., & Lewis, A. K. (2019) · Neurology · doi:10.1212/wnl.0000000000006750 · Cited by 163
Determination of death by neurologic criteria around the world
Lewis, A. K., Bakkar, A., Kreiger-Benson, E., Kumpfbeck, A. R., Liebman, J., Shemie, S. D., Sung, G. Y., Torrance, S., & Greer, D. M. (2020) · Neurology · doi:10.1212/wnl.0000000000009888 · Cited by 143
S3-Leitlinie Sepsis – Prävention, Diagnose, Therapie und Nachsorge
Deutsche Sepsis Gesellschaft e., V., Brunkhorst, F. M., Weigand, M. A., Pletz, M. W., Gastmeier, P., Lemmen, S., Meier‐Hellmann, A., Ragaller, M., Weyland, A., Marx, G., et al. (2020) · Medizinische Klinik - Intensivmedizin und Notfallmedizin · doi:10.1007/s00063-020-00685-0 · Cited by 128
Myburgh, J., Abillama, F. F., Chiumello, D., Dobb, G. J., Jacobe, S. J., Kleinpell, R. M., Koh, Y., Martin, C. M., Michalsen, A., Pelosi, P. P., et al. (2016) · Journal of Critical Care · doi:10.1016/j.jcrc.2016.04.017 · Cited by 118
Self-citationMaldonado, F., Rafael, F. J., Shinall, M. C., & Ely, E. W. (2020) · Critical Care Medicine · doi:10.1097/ccm.0000000000004475 · Cited by 112
Clinical Presentation and Management of Severe Ebola Virus Disease
West, T. E., & Arnim, A. V. S. A.-V. (2014) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201410-481ps · Cited by 94
Phua, J., Joynt, G. M., Nishimura, M., Deng, Y., Myatra, S. N., Chan, Y. H., Bình, N. G., Tan, C. C., Faruq, M. O., Arabi, Y. M., et al. (2016) · Intensive Care Medicine · doi:10.1007/s00134-016-4347-y · Cited by 90
Self-citationWilson, M. E., Majzoub, A. M., Dobler, C. C., Curtis, J. R., Nayfeh, T., Thorsteinsdottir, B., Barwise, A. K., Tilburt, J. C., Gajic, O., Montori, V. M., et al. (2018) · Critical Care Medicine · doi:10.1097/ccm.0000000000003082 · Cited by 84
Self-citationMathur, R., Macaden, S. C., Simha, N., & Rajagopal, M. R. (2018) · Indian Journal of Critical Care Medicine · doi:10.4103/ijccm.ijccm_165_18 · Cited by 80
Responsible Research Publication: International Standards for Editors
Wager, E., & Kleinert, S. (2014) · PRILOZI · doi:10.1515/prilozi-2015-0006 · Cited by 79
Lesieur, O., Leloup, M., Gonzalez, F., & Mamzer, M. (2015) · Annals of Intensive Care · doi:10.1186/s13613-015-0056-x · Cited by 79
Ethical challenges in resuscitation
Mentzelopoulos, S. D., Slowther, A.-M., Fritz, Z., Sandroni, C., Xanthos, T., Callaway, C., Perkins, G. D., Newgard, C., Ischaki, E., Greif, R., et al. (2018) · Intensive Care Medicine · doi:10.1007/s00134-018-5202-0 · Cited by 71
Organ Support After Death by Neurologic Criteria in Pediatric Patients
Lewis, A. K., Adams, N., Chopra, A., & Kirschen, M. P. (2017) · Critical Care Medicine · doi:10.1097/ccm.0000000000002452 · Cited by 68
Physician-Assisted Suicide and Euthanasia
Sprung, C. L., Somerville, M. A., Radbruch, L., Collet, N. S., Duttge, G., Piva, J. P., Antonelli, M. M., Sulmasy, D. P., Lemmens, W., & Ely, E. W. (2018) · Journal of Palliative Care · doi:10.1177/0825859718777325 · Cited by 74
Self-citationPhysician-Assisted Suicide and Euthanasia in the ICU: A Dialogue on Core Ethical Issues*
Goligher, E. C., Ely, E. W., Sulmasy, D. P., Bakker, J., Raphael, J., Volandes, A. E., Patel, B., Payne, K., Hosie, A., Churchill, L. R., et al. (2017) · Critical Care Medicine · doi:10.1097/ccm.0000000000001818 · Cited by 66
Current controversies in brain death determination
Lewis, A. K., & Greer, D. M. (2017) · Nature Reviews Neurology · doi:10.1038/nrneurol.2017.72 · Cited by 63
Shouldn't Dead Be Dead?: The Search for a Uniform Definition of Death
Lewis, A. K., Cahn-Fuller, K. L., & Caplan, A. L. (2017) · The Journal of Law Medicine & Ethics · doi:10.1177/1073110517703105 · Cited by 60
Cox, C. E., Wysham, N. G., Walton, B., Jones, D., Cass, B., Tobin, M., Jonsson, M., Kahn, J. M., White, D. B., Hough, C. L., et al. (2015) · Annals of Intensive Care · doi:10.1186/s13613-015-0045-0 · Cited by 44
Short, S. R., & Thienprayoon, R. (2018) · Translational Pediatrics · doi:10.21037/tp.2018.09.11 · Cited by 45
A National Study of Life-Sustaining Treatments in South Korea: What Factors Affect Decision-Making?
Park, S.-Y., Lee, B., Seon, J.-Y., & Oh, I. (2020) · Cancer Research and Treatment · doi:10.4143/crt.2020.803 · Cited by 43
Long, A. C., Brumback, L. C., Curtis, J. R., Avidan, A., Baras, M., ROBERTIS, E. D., Efferen, L. S., Engelberg, R. A., Kross, E. K., Michalsen, A., et al. (2019) · Critical Care Medicine · doi:10.1097/ccm.0000000000003922 · Cited by 43
Self-citationWilson, M. E., Mittal, A., Karki, B., Dobler, C. C., Wahab, A., Curtis, J. R., Erwin, P. J., Majzoub, A. M., Montori, V. M., Gajic, O., et al. (2019) · Intensive Care Medicine · doi:10.1007/s00134-019-05828-2 · Cited by 43
Self-citationTang, S. T., Huang, C.-C., Hu, T., Chou, W., Chuang, L., & Chiang, M.-C. (2021) · Critical Care · doi:10.1186/s13054-021-03719-x · Cited by 45
Reconciling the Case of Jahi McMath
Lewis, A. K. (2018) · Neurocritical Care · doi:10.1007/s12028-018-0561-5 · Cited by 42
Connolly, C., Miskolci, O., Phelan, D. M. J., & Buggy, D. J. (2016) · British Journal of Anaesthesia · doi:10.1093/bja/aew109 · Cited by 41
Practice Recommendations for End-of-Life Care in the Intensive Care Unit
Jensen, H. I., Halvorsen, K., Jerpseth, H., Fridh, I., & Lind, R. (2020) · Critical Care Nurse · doi:10.4037/ccn2020834 · Cited by 41
Portrayal of Brain Death in Film and Television
Lewis, A. K., Weaver, J., & Caplan, A. L. (2016) · American Journal of Transplantation · doi:10.1111/ajt.14016 · Cited by 39
Joynt, G. M., Gopalan, D. P., Argent, A., Chetty, S., Wise, R., Lai, V. K. W., Hodgson, E., Lee, A. L., Joubert, I., Mokgokong, S., et al. (2019) · South African Medical Journal · doi:10.7196/samj.2019.v109i8b.13947 · Cited by 37
Self-citationRubio, O., Arnau, A., Cano, S., Subirá, C., Balerdi, B., Perea, M. E., Fernández-Vivas, M., Barber, M., Llamas, N., Altaba, S., et al. (2018) · Journal of Intensive Care · doi:10.1186/s40560-018-0283-y · Cited by 36
Self-citationEthik der Reanimation und Entscheidungen am Lebensende
Bossaert, L. L., Perkins, G. D., Askitopoulou, H., Raffay, V. I., Greif, R., Haywood, K. L., Mentzelopoulos, S. D., Nolan, J. P., de Voorde, P. V., & Xanthos, T. T. (2015) · Notfall + Rettungsmedizin · doi:10.1007/s10049-015-0083-z · Cited by 42
Špoljar, D., Ćurković, M., Gastmans, C., Gordijn, B., Vrkić, D., Jozepović, A., Vuletić, S. A., Tonković, D., & Borovečki, A. (2020) · Journal of Critical Care · doi:10.1016/j.jcrc.2020.03.010 · Cited by 35
Ethik der Reanimation und Entscheidungen am Lebensende
Mentzelopoulos, S. D., Couper, K., de Voorde, P. V., Druwé, P., Blom, M. T., Perkins, G. D., Lulić, I., Djakow, J., Raffay, V. I., Lilja, G., et al. (2021) · Notfall + Rettungsmedizin · doi:10.1007/s10049-021-00888-8 · Cited by 32
Non-Faith-Based Arguments against Physician-Assisted Suicide and Euthanasia
Sulmasy, D. P., Travaline, J. M., Mitchell, L. A., & Ely, E. W. (2016) · The Linacre Quarterly · doi:10.1080/00243639.2016.1201375 · Cited by 33
Estella, Á., Saralegui, I., Sanchiz, O. R., Hernández-Tejedor, A., Camps, V. L., Martín, M. C., Pericas, L. C., Burralló, N. M., Núñez, M. R., & Monzón, J. L. (2019) · Medicina Intensiva · doi:10.1016/j.medin.2019.07.006 · Cited by 34
The Quality of End-of-Life Care among ICU versus Ward Decedents
Rolnick, J. A., Ersek, M. T., Wachterman, M. W., & Halpern, S. D. (2020) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201907-1423oc · Cited by 36
Kerckhoffs, M. C., Senekal, J., van Dijk, D., Artigas, A., Butler, J., Michalsen, A., van Mol, M. M. C., Moreno, R. P., da Silva, F. P., Picetti, E., et al. (2020) · Critical Care Medicine · doi:10.1097/ccm.0000000000004221 · Cited by 29
Self-citationS3-Leitlinie Sepsis – Prävention, Diagnose, Therapie und Nachsorge
Deutsche Sepsis Gesellschaft e., V., Brunkhorst, F. M., Weigand, M. A., Pletz, M. W., Gastmeier, P., Lemmen, S., Meier‐Hellmann, A., Ragaller, M., Weyland, A., Marx, G., et al. (2020) · Medizinische Klinik - Intensivmedizin und Notfallmedizin · doi:10.1007/s00063-020-00671-6 · Cited by 31
Shapiro, M. C., Donohue, P., Kudchadkar, S. R., Hutton, N., & Boss, R. D. (2017) · Pediatric Critical Care Medicine · doi:10.1097/pcc.0000000000001247 · Cited by 30
The quality of dying and death for patients in intensive care units: a single center pilot study
Choi, Y., Park, M., Kang, D. H., Lee, J., Moon, J. Y., & Heejoon, A. H. N. (2019) · Acute and Critical Care · doi:10.4266/acc.2018.00374 · Cited by 29
Gupta, S., Kumar, A., Mathur, R., Gursahani, R., Bhatnagar, S., Deodhar, J. K., Nasa, P., Mani, R. K., Salins, N. S., Kulkarni, P., et al. (2024) · Indian Journal of Critical Care Medicine · doi:10.5005/jp-journals-10071-24661 · Cited by 31
S3-Leitlinie Sepsis – Prävention, Diagnose, Therapie und Nachsorge – Update 2025
Brunkhorst, F. M., Adamzik, M., Axer, H., Bauer, M. W., Bode, C., Bone, H.-G., Brenner, T., Bucher, M., David, S., Dietrich, M., et al. (2025) · Medizinische Klinik - Intensivmedizin und Notfallmedizin · doi:10.1007/s00063-025-01317-1 · Cited by 35
Blatter, R., Amacher, S. A., Bohren, C., Becker, C., Beck, K., Groß, S., Tisljar, K., Sutter, R., Marsch, S. C. U., & Hunziker, S. (2022) · Annals of Intensive Care · doi:10.1186/s13613-022-01048-y · Cited by 28
Palliative care in the ICU of 2050: past is prologue
Mathews, K. S., & Nelson, J. E. (2017) · Intensive Care Medicine · doi:10.1007/s00134-017-4828-7 · Cited by 27
Family presence during resuscitation: A concise narrative review
ROBERTIS, E. D., Romano, G. M., Hinkelbein, J., Piazza, O., & Sorriento, G. (2017) · Trends in Anaesthesia and Critical Care · doi:10.1016/j.tacc.2017.06.001 · Cited by 27
Global Comparison of Communication of End-of-Life Decisions in the ICU
Feldman, C. H., Sprung, C. L., Mentzelopoulos, S. D., Pohrt, A., Hartog, C. S., Danbury, C. M., Weiß, M., Avidan, A., Estella, Á., Joynt, G. M., et al. (2022) · CHEST Journal · doi:10.1016/j.chest.2022.05.007 · Cited by 27
Self-citationPhysician Power to Declare Death by Neurologic Criteria Threatened
Lewis, A. K., & Pope, T. M. (2017) · Neurocritical Care · doi:10.1007/s12028-017-0375-x · Cited by 26
Rosenwohl-Mack, S., Dohan, D. P., Matthews, T., Batten, J. N., & Dzeng, E. W. (2020) · Journal of General Internal Medicine · doi:10.1007/s11606-020-06314-y · Cited by 26
Opportunities to maximize value with integrated palliative care
Bergman, J., & Laviana, A. A. (2016) · Journal of Multidisciplinary Healthcare · doi:10.2147/jmdh.s90822 · Cited by 25
van Veen, E., van der Jagt, M., Citerio, G., Stocchetti, N., Epker, J. L., Gommers, D. A. M. P. J., Burdorf, A., Menon, D. K., Maas, A. I. R., Lingsma, H. F., et al. (2020) · Journal of Critical Care · doi:10.1016/j.jcrc.2020.04.001 · Cited by 25
Quenot, J., Ecarnot, F., Meunier‐Beillard, N., Dargent, A., Large, A., Andreu, P., & Rigaud, J. (2017) · Annals of Translational Medicine · doi:10.21037/atm.2017.08.08 · Cited by 25
Sprung, C. L., Jennerich, A. L., Joynt, G. M., Michalsen, A., Curtis, J. R., Efferen, L. S., Leonard, S., Metnitz, B., Mikstacki, A., Patil, N., et al. (2021) · Journal of Palliative Care · doi:10.1177/08258597211002308 · Cited by 23
Self-citationLimiting futile therapy as part of end-of-life care in intensive care units
Damps, M., Gajda, M., Stołtny, L., Kowalska, M., & Kucewicz-Czech, E. M. (2022) · Anaesthesiology Intensive Therapy · doi:10.5114/ait.2022.119124 · Cited by 22
End-of-life practices in 11 German intensive care units
Denke, C., Jaschinski, U., Rießen, R., Bercker, S., Spies, C., Ragaller, M., Weiss, M., Dey, K., Michalsen, A., Briegel, J., et al. (2022) · Medizinische Klinik - Intensivmedizin und Notfallmedizin · doi:10.1007/s00063-022-00961-1 · Cited by 22
Self-citationLo, M.-L., Huang, C.-C., Hu, T., Chou, W., Chuang, L., Chiang, M.-C., Wen, F., & Tang, S. T. (2020) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2020.07.002 · Cited by 22
Quenot, J., Ecarnot, F., Meunier‐Beillard, N., Dargent, A., Large, A., Andreu, P., & Rigaud, J. (2017) · Annals of Translational Medicine · doi:10.21037/atm.2017.04.15 · Cited by 21
Limitation of therapeutic effort experienced by intensive care nurses
Velarde‐García, J. F., González, R. L., González‐Hervías, R., Cardenete-Reyes, C., Álvarez‐Embarba, B., & Palacios‐Ceña, D. (2016) · Nursing Ethics · doi:10.1177/0969733016679471 · Cited by 21
Advance Directives in the Neurocritically Ill: A Systematic Review
Sutter, R., Meyer-Zehnder, B., Baumann, S. M., Marsch, S. C. U., & Pargger, H. (2020) · Critical Care Medicine · doi:10.1097/ccm.0000000000004388 · Cited by 21
Contentious Ethical and Legal Aspects of Determination of Brain Death
Lewis, A. K. (2018) · Seminars in Neurology · doi:10.1055/s-0038-1668075 · Cited by 20
Reasons for physician‐related variability in end‐of‐life decision‐making in intensive care
Syrous, A. N., Malmgren, J., Hergès, H. O., Olausson, S., Redfors, M. K., Ågård, A., & Block, L. (2021) · Acta Anaesthesiologica Scandinavica · doi:10.1111/aas.13842 · Cited by 20
Mentzelopoulos, S. D., Chen, S., Nates, J. L., Kruser, J. M., Hartog, C. S., Michalsen, A., Efstathiou, N., Joynt, G. M., Lobo, S. M., Avidan, A., et al. (2022) · Critical Care · doi:10.1186/s13054-022-03971-9 · Cited by 20
Self-citationAlmalki, N. J., Boyle, B., & O’Halloran, P. D. (2024) · BMC Palliative Care · doi:10.1186/s12904-024-01413-7 · Cited by 20
Ćurković, M., Brajković, L., Jozepović, A., Tonković, D., Župan, Ž., Karanović, N., & Borovečki, A. (2021) · Journal of Bioethical Inquiry · doi:10.1007/s11673-021-10128-w · Cited by 19
Rubić, F., Ćurković, M., Brajković, L., Nevajdić, B., Novak, M., Filipović‐Grčić, B., Meštrović, J., Tomulić, K. L., Peter, B., & Borovečki, A. (2022) · Medicina · doi:10.3390/medicina58020250 · Cited by 19
Barriers and Facilitators to End-of-Life Care Delivery in ICUs: A Qualitative Study
Janczewski, L. M., Chandrasekaran, A., Abahuje, E. A. E., Ko, B., Slocum, J. D., Tesorero, K., Nguyen, M. L. T., Yang, S., Strong, E. A., Bhakta, K., et al. (2024) · Critical Care Medicine · doi:10.1097/ccm.0000000000006235 · Cited by 22
Quenot, J., Large, A., Meunier‐Beillard, N., Pugliesi, P.-S., Rollet, P., Toitot, A., Andreu, P., Devilliers, H., Marchalot, A., Ecarnot, F., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0222039 · Cited by 19
Compassionate care during withdrawal of treatment: A secondary analysis of ICU nurses' experiences
Efstathiou, N., & Ives, J. (2017) · Nursing Ethics · doi:10.1177/0969733016687159 · Cited by 19
Team-family conflicts over end-of-life decisions in ICU: A survey of French physicians’ beliefs
Giabicani, M., Arditty, L., Mamzer, M., Fournel, I., Ecarnot, F., Meunier‐Beillard, N., Bruneel, F., Weiss, E., Spranzi, M., Rigaud, J., et al. (2023) · PLoS ONE · doi:10.1371/journal.pone.0284756 · Cited by 18
Coventry, A., Ford, R. C., Rosenberg, J. P., & McInnes, E. (2020) · Journal of Advanced Nursing · doi:10.1111/jan.14416 · Cited by 18
Determination of Brain Death/Death by Neurologic Criteria in Countries in Asia and the Pacific
Lewis, A. K., Liebman, J., Bakkar, A., Kreiger-Benson, E., Kumpfbeck, A. R., Shemie, S. D., Sung, G. Y., Torrance, S., & Greer, D. M. (2020) · Journal of Clinical Neurology · doi:10.3988/jcn.2020.16.3.480 · Cited by 17
Bartkowska‐Śniatkowska, A., Byrska-Maciejasz, E., Cettler, M., Damps, M., Jarosz, K., Mierzewska-Schmidt, M., Migdał, M., Ożóg-Zabolska, I., Piotrowski, A., Rawicz, M., et al. (2021) · Anaesthesiology Intensive Therapy · doi:10.5114/ait.2021.111451 · Cited by 17
Wen, F., Prigerson, H. G., Hu, T., Huang, C.-C., Chou, W., Chuang, L., Chiang, M.-C., & Tang, S. T. (2024) · Critical Care Medicine · doi:10.1097/ccm.0000000000006199 · Cited by 18
Gristina, G. R., Busatta, L., & Piccinni, M. (2019) · Minerva Anestesiologica · doi:10.23736/s0375-9393.18.13179-8 · Cited by 17
On behalf on the Working Group Epidemiology and Ethics of the German Society of Anesthesiology and Intensive Care Medicine (DGAI), Weiß, M., Michalsen, A., Toenjes, A., Porzsolt, F., Bein, T., Theisen, M., Brinkmann, A., Groesdonk, H. V., Putensen, C., et al. (2017) · BMC Anesthesiology · doi:10.1186/s12871-017-0384-5 · Cited by 15
Self-citationBruno, R. R., Wernly, B., Beil, M., Muessig, J. M., Rahmel, T., Graf, T., Meybohm, P., Schaller, S. J., Allgäuer, S., Franz, M., et al. (2020) · Journal of Critical Care · doi:10.1016/j.jcrc.2020.07.024 · Cited by 15
Medicolegal Complications of Apnoea Testing for Determination of Brain Death
Lewis, A. K., & Greer, D. M. (2018) · Journal of Bioethical Inquiry · doi:10.1007/s11673-018-9863-8 · Cited by 14
Hastening Death in Canadian ICUs: End-of-Life Care in the Era of Medical Assistance in Dying*
Andersen, S. K., Stewart, S., Leier, B., Alden, L. E., Townsend, D. R., & Garros, D. (2021) · Critical Care Medicine · doi:10.1097/ccm.0000000000005359 · Cited by 14
Wen, F., Chou, W., Huang, C.-C., Hu, T., Chiang, M.-C., Chuang, L., & Tang, S. T. (2022) · Critical Care · doi:10.1186/s13054-022-03981-7 · Cited by 16
Worldwide end-of-life practice for patients in ICUs
Wong, W., Phua, J., & Joynt, G. M. (2018) · Current Opinion in Anaesthesiology · doi:10.1097/aco.0000000000000563 · Cited by 14
Self-citationQuality of dying and death in intensive care units: family satisfaction
Wen, F., Chiang, M.-C., Huang, C.-C., Hu, T., Chou, W., Chuang, L., & Tang, S. T. (2023) · BMJ Supportive & Palliative Care · doi:10.1136/spcare-2022-003950 · Cited by 13
Variability in forgoing life-sustaining treatments: reasons and recommendations
Sprung, C. L., Rusínová, K., & Ranzani, O. (2015) · Intensive Care Medicine · doi:10.1007/s00134-015-3868-0 · Cited by 13
Self-citationStachulski, F., Siegerink, B., & Bösel, J. (2020) · Journal of Intensive Care Medicine · doi:10.1177/0885066620906795 · Cited by 12
Jawiche, R. E., Hallit, S. R., Tarabey, L., & Abou-Mrad, F. (2020) · BMC Medical Ethics · doi:10.1186/s12910-020-00525-y · Cited by 12
Cullum, K., Madani, C., Cutler, E. R., & Reavis, K. J. (2022) · Respiratory Care · doi:10.4187/respcare.09249 · Cited by 11
Long-Term Outcomes in Critically Ill Septic Patients Who Survived Cardiopulmonary Resuscitation*
Chao, P.-W., Chu, H., Chen, Y., Shih, Y.-N., Kuo, S., Li, S., Ou, S., & Shih, C.-J. (2016) · Critical Care Medicine · doi:10.1097/ccm.0000000000001608 · Cited by 11
Joynt, G. M., Gopalan, D. P., Argent, A., Chetty, S., Wise, R., Lai, V. K. W., Hodgson, E., Lee, A., Joubert, I., Mokgokong, S., et al. (2019) · Southern African Journal of Critical Care · doi:10.7196/sajcc.2019.v35i1b.383 · Cited by 17
Self-citationEstella, Á., Saralegui, I., Sanchiz, O. R., Hernández-Tejedor, A., Camps, V. L., Martín, M. C., Pericas, L. C., Burralló, N. M., Núñez, M. R., & Monzón, J. L. (2019) · Medicina Intensiva (English Edition) · doi:10.1016/j.medine.2019.07.003 · Cited by 11
Association of medical futility with do-not-resuscitate (DNR) code status in hospitalised patients
Becker, C., Manzelli, A., Marti, A., Cam, H., Beck, K., Vincent, A., Keller, A., Bassetti, S., Rikli, D. A., Schaefert, R., et al. (2021) · Journal of Medical Ethics · doi:10.1136/medethics-2020-106977 · Cited by 11
Constitutional and legal protection for life support limitation in India
Mani, R. (2015) · Indian Journal of Palliative Care · doi:10.4103/0973-1075.164903 · Cited by 11
White, B. P., Willmott, L., Cartwright, C., Parker, M., & Williams, G. M. (2016) · Critical Care and Resuscitation · doi:10.1016/s1441-2772(23)01000-1 · Cited by 11
Smirdec, M., Jourdain, M., Guastella, V., Lambert, C., Richard, J., Argaud, L., Jaber, S., Klouche, K., Médard, A., Reignier, J., et al. (2020) · Critical Care · doi:10.1186/s13054-020-03402-7 · Cited by 10
Cortegiani, A., Ippolito, M., & Mercadante, S. (2024) · Anesthesiology Clinics · doi:10.1016/j.anclin.2024.02.008 · Cited by 10
Metadata
- Authors
- Sprung, C. L., Truog, R. D., Curtis, J. R., Joynt, G. M., Baras, M., Michalsen, A., Briegel, J., Kesecioglu, J., Efferen, L., De Robertis, E., Bulpa, P., Metnitz, P., Patil, N., Hawryluck, L., Manthous, C., Moreno, R., Leonard, S., Hill, N. S., Wennberg, E., McDermid, R. C., Mikstacki, A., Mularski, R. A., Hartog, C. S., & Avidan, A.
- Affiliations
- Hadassah Medical Center (IL)
- Boston Children's Hospital (US)
- University of Washington (US)
- Chinese University of Hong Kong (HK)
- Hebrew University of Jerusalem (IL)
- Department of Anaesthesiology and Critical Care Medicine, Tettnang Hospital, Tettnang, Germany
- Ludwig-Maximilians-Universität München (DE)
- Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht, The Netherlands
- South Nassau Communities Hospital (US)
- Department of Neurosciences, Reproductive and Odontostomatologic Sciences, University of Naples, Federico II, Naples, Italy
- UCLouvain (BE)
- University of Vienna (AT)
- Brigham and Women's Hospital (US)
- Toronto Western Hospital (CA)
- Medical Intensive Care Unit, Lawrence and Memorial Hospital, New London, Connecticut
- Unidade Local de Saúde de São José (PT)
- King's College Hospital (GB)
- Tufts Medical Center (US)
- University of Gothenburg (SE)
- University of Alberta (CA)
- Department of Anaesthesiology and Intensive Therapy, Regional Hospital, Poznań, Poland
- Kaiser Permanente (US)
- Jena University Hospital (DE)
- Corresponding author
- Sprung, Charles L.
- ORCID
- Venue
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2014-10-01
- Volume
- 190
- Issue
- 8
- Pages
- 855-866
- ISSN
- 1073-449X (ISSN-L)
- 1535-4970
- OpenAlex
- W2110407084
- Cited by
- 250
- References
- 43
- Citations by year
- 2026: 13 · 2025: 10 · 2024: 19 · 2023: 16 · 2022: 30 · 2021: 26 · 2020: 40 · 2019: 19 · 2018: 16 · 2017: 19 · 2016: 16 · 2015: 22 · 2014: 4
- FWCI
- 20.14
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Respiratory and Critical Care Medicine (publishedVersion)
- PubMed (publishedVersion)
- Digital Access to Libraries (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics and bioethics in healthcare
- Keywords
- end-of-life care, critically ill patients, intensive care unit, international consensus, ethical principles, withholding and withdrawing life-sustaining treatment, informed consent, cardiopulmonary resuscitation, shared decision-making, brain death, palliative care
- MeSH terms
- Brain Death, Critical Care, Decision Making, Humans, Informed Consent, Intensive Care Units, International Cooperation, Palliative Care, Terminal Care, Critical Illness, Withholding Treatment
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review