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Silica-Precipitating Peptides Isolated from a Combinatorial Phage Display Peptide Library
Abstract
Many biological organisms contain specialized structures composed of inorganic materials. Cellular processes in vivo facilitate the organized assembly of mineral building blocks into complex structures. The structural hierarchy and complexity across a range of length scales are providing new ideas and concepts for materials chemistry. Proteins that direct biomineralization can be used to control the production of nanostructured materials and facilitate the fabrication of new structures. Here, we demonstrate that some of the silica-binding peptides isolated from a combinatorial phage peptide display library can be used in precipitating silica from a solution of silicic acid. The results described in this report demonstrate that peptides displayed by phages act as templates in inorganic material synthesis and provide a means of understanding how some of the biological systems may be carrying out materials chemistry in vivo.
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Citations
Cited by
Gower, L. B. (2008) · Chemical Reviews · doi:10.1021/cr800443h · Cited by 1,086
On the role(s) of additives in bioinspired silicification
Patwardhan, S. V., Clarson, S. J., & Perry, C. C. (2005) · Chemical Communications · doi:10.1039/b416926c · Cited by 217
Self-citationBiodegradable Thermoplastic Polyurethanes Incorporating Polyhedral Oligosilsesquioxane
Knight, P. T., Lee, K. M., Qin, H., & Mather, P. T. (2008) · Biomacromolecules · doi:10.1021/bm8004935 · Cited by 141
Metadata
- Authors
- Naik, R. R., Brott, L. L., Clarson, S. J., & Stone, M. O.
- Venue
- Journal of Nanoscience and Nanotechnology
- Publisher
- American Scientific Publishers
- Published
- 2002-02-01
- Volume
- 2
- Issue
- 1
- Pages
- 95-100
- ISSN
- 1533-4880 (ISSN-L)
- 0000-0000
- OpenAlex
- W2072405035
- Cited by
- 302
- References
- 0
- FWCI
- 9.78
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.