AN ELECTROPHORETIC STUDY OF THE PROTEIN COMPONENTS IN CEREBROSPINAL FLUID AND THEIR RELATIONSHIP TO THE SERUM PROTEINS 1
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Multiple sclerosis is a neurological disorder of the central nervous system resulting from an autoimmune attack on CNS white matter.
“Multiple sclerosis [MS, (MIM 126200)] is a neurological disorder of the central nervous system (CNS), resulting from an autoimmune attack on CNS white matter.”
From Genome‐wide association studies of multiple sclerosis (2018) · cites this paper as [4]
The Results (page unavailable) examine cerebrospinal fluid from five people with multiple sclerosis, supporting the paper’s relevance to the disease. Neither those results nor the Discussion passage on antibody production—which concerns neurosyphilis—states that MS results from an autoimmune attack on CNS white matter. (LLM, conf=0.76)
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Research works printed but not linked: 8
- Merritt, H. H., and Fremont-Smiiitlh, F., Cerebrospinal Fluid. WV. B. Saunders Co., Philadelphia, 1937.
- Freund, J., Accumulation of antibodies in the central nervous system. J. Exper. Med., 1930, 51, 889.
- Tiselius, A., A new apparatus for electrophoretic analysis of colloidal mixtures. Tr. Faraday Soc., 1937, 33, 524.
- Kabat, E. A., Landow, H., and Moore, D. H., Electro- phoretic patterns of concentrated cerebrospinal fluid. Proc. Soc. Exper. Biol. and Med., 1942, 49, 260.
- Longsworth, L. G., A modification of the schlieren metlhod for use in electroplhoretic analyses. J. Am. Chem. Soc., 1939, 61, 529.
- Kabat, E. A., The molecular weight of antibodies. J. Exper. Med., 1939, 69, 103.
- Katzenelbogen, S., The Cerebrospinial Fluid and its Relation to the Blood. Johns Hopkins Press, Baltimore, 1935.
- Sabin, F. R., Cellular reactions to a dye-protein with a concept of the mechaniisnm of antibody formation. J. Exper. MIed., 1939, 70, 67.
Cited by
Sorted by citations
Transthyretin: A multifaceted protein
Vieira, M., & Saraiva, M. J. (2014) · BioMolecular Concepts · doi:10.1515/bmc-2013-0038 · Cited by 185 · see citing works
Genome‐wide association studies of multiple sclerosis
Cotsapas, C., & Mitrovic, M. (2018) · Clinical & Translational Immunology · doi:10.1002/cti2.1018 · Cited by 89 · see citing works
- Authors
- Kabat, E. A., Moore, D. H., & Landow, H.
- Affiliations
- Columbia University (US)
- The Neurological Institute (US)
- ORCID
- Moore, Dan H.
- Venue
- Journal of Clinical Investigation
- Published
- 1942-09-01
- Volume
- 21
- Issue
- 5
- Pages
- 571-577
- ISSN
- 0021-9738 (ISSN-L)
- PMC
- PMC435175
- OpenAlex
- W2105421015
- Cited by
- 458
- References
- 0
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 8 · 2023: 5 · 2022: 9 · 2021: 10 · 2020: 3 · 2019: 14 · 2018: 9 · 2017: 15 · 2016: 12 · 2015: 11 · 2014: 12 · 2013: 14 · 2012: 8
- FWCI
- 1.45
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Cerebrospinal fluid and hydrocephalus
- Physical Sciences › Chemistry › Spectroscopy › Advanced Proteomics Techniques and Applications
- Health Sciences › Medicine › Physiology › Clinical Laboratory Practices and Quality Control
- Keywords
- cerebrospinal fluid, serum proteins, protein components, electrophoretic analysis, cerebrospinal fluid protein
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