CONGENITAL METHEMOGLOBINEMIA. A CLINICAL AND BIOCHEMICAL STUDY OF A CASE 1
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Every 24 h, 3% of hemoglobin undergoes autoxidation, producing methemoglobin and superoxide radical anion.
“Every 24 h, 3% of Hb undergoes autoxidation, producing metHb and superoxide radical anion (Eq. 1) (50).”
From Red Blood Cell Function and Dysfunction: Redox Regulation, Nitric Oxide Metabolism, Anemia (2017) · cites this paper as [50]
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References 32 · Cited by 90
Research works printed but not linked: 17
- Hitzenberger, K., Autotoxische Zyanose (Intraglobu- lire Methamoglobinamie). Wien. Arch. inn. Med., 1932, 23, 85.
- Dieckmann, W. J., Methemoglobinemia. Arch. Int. Med., 1932, 50, 574.
- Van Thienen, G. J., Methaemoglobinaemia. Nederl. tijdschr. v. geneesk., 1933, 77, 1086.
- Van Heukelom, S., Intraglobulaire congenitale fami- liaire methemoglobinaemia. Geneesk. tijdschr. Nederl.-Indie, 1937, 77, 3054.
- Lian, C., Frumusan, P., and Sassier, M., Methemo- globinemie congenitale et familiale. Action favor- able de l'acide ascorbique. Bull. et mem. Soc. med. d. hop. de Paris, 1939, 55, 1194.
- Graybiel, A., Lilienthal, J. L., and Riley, R. L., The report of a case of idiopathic congenital (and probably familial) methemoglobinemia. Bull. Johns Hopkins Hosp., 1945, 76, 155.
- Sievers, R. F., and Ryon, J. B., Congenital idio- pathic methemoglobinemia; favorable response to ascorbic acid therapy. Arch. Int. Med., 1945, 76, 299.
- Slosse, A., and Wybauw, R., Un cas de methemo- globinemie idiopathique. Ann. et bull. Soc. roy. d. sc. med. et nat. Brux., 1912, 70, 206.
- Litarczek, G., Aubert, H., Cosmulesco, I., Comanesco, V., and Litarczek, S., Sur un cas de cyanose auto- toxique par methimoglobinemie intraglobulaire. Sang, 1930, 4, 188.
- Leiner, G., and Minibeck, H., Ein Fall von intra- globularer Methaemoglobinaemie. Wien. klin. Wchnschr., 1935, 48, 1547.
- Gibson, Q. H., and Harrison, D. C., Familial idio- pathic methaemoglobinaemia, five cases in one family. Lancet, 1947, 2, 941.
- Warburg, O., Kubowitz, F., and Christian, W., tUber die katalytische Wirkung von Methylenblau in lebenden Zellen. Biochem. Ztschr., 1930, 227, 245.
- McKee, R. W., Omsbee, R. A., Anfinsen, C. B., Geiman, Q. M., and Ball, E. G., Studies on ma- larial parasites. VI. The chemistry and metabo- lism of normal and parasitized (P. Knowlesi) monkey blood. J. Exper. Med., 1946, 84, 569.
- Peters, J. P., and Van Slyke, D. D., Quantitative Clinical Chemistry, Vol. I, Interpretations. Wil- liams and Wilkins Co., Baltimore, 1932, pp. 1097, 1098.
- Barrenscheen, H. K., and Vasarhelyi, B., Unter- suchungen uber die Glykolyse des Blutes. II. Pyrophosphatfraktion und Glykolyse. Biochem. Ztschr., 1931, 230, 330.
- Williams, J. R., and Challis, F. E., Methylene blue as an antidote for anilin dye poisoning. J. Lab. & Clin. Med., 1933, 19, 166.
- Fujita, A., and Numata, I., tVber die jodometrische Bestimmung des Glutathions in Geweben. Biochem. Ztschr., 1938, 299, 249.
- Authors
- Eder, H. A., Finch, C., & McKee, R. W.
- Affiliations
- Harvard University (US)
- Venue
- Journal of Clinical Investigation
- Published
- 1949-03-01
- Volume
- 28
- Issue
- 2
- Pages
- 265-272
- ISSN
- 0021-9738 (ISSN-L)
- PMC
- PMC439597
- OpenAlex
- W2061890164
- Cited by
- 90
- References
- 32
- Citations by year
- 2026: 2 · 2023: 2 · 2022: 3 · 2021: 1 · 2020: 2 · 2016: 1 · 2015: 2 · 2013: 1
- FWCI
- 5.95
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Clinical Investigation (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Methemoglobinemia and Tumor Lysis Syndrome
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Hemoglobin structure and function
- Health Sciences › Medicine › Genetics › Hemoglobinopathies and Related Disorders
- Keywords
- congenital methemoglobinemia, methemoglobinemia, hemoglobin, clinical features, biochemical diagnosis
- MeSH terms
- Humans, Methemoglobinemia, Research
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