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Cited by 256

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

The Effect of Angiotensin II on the Blood Pressure in Humans with Hypertensive Disease*

Open access
Kaplan, Norman M., Silah, Jack G.·1964·Journal of Clinical Investigation

Abstract

A reduced sensitivity to the pressor effect of exogenous angiotensin 1 has been observed in dogs with increased levels of endogenous angiotensinlike activity (1). Patients with secondary hyperaldosteronism, where levels of endogenous angiotensin are thought to be elevated, also have a reduced pressor responsiveness to exogenous angiotensin, but not to l-norepinephrine (2, 3). A reduced pressor responsiveness to angiotensin might then be expected with renovascular hypertension, which is said to be associated with increased levels of circulating renin and angiotensin (4). The pressor responses to exogenous angiotensin and, in some patients, to l-norepinephrine were initially examined in a variety of experimental and pathological situations where the levels of endogenous angiotensin have either been shown or are believed to be altered. Patients with various hypertensive diseases were then studied. The results suggest that the pressor responsiveness to angiotensin may be a useful clinical test for the diagnosis of renovascular hypertension.

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Crossref · 10.1172/jci104951

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Metadata

Authors
Kaplan, N. M., & Silah, J. G.
Venue
Journal of Clinical Investigation
Published
1964-04-01
Volume
43
Issue
4
Pages
659-669
ISSN
0021-9738 (ISSN-L)
OpenAlex
W2109236972
Cited by
256
References
6
FWCI
22.51
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The Effect of Angiotensin II on the Blood Pressure in Humans with Hypertensive Disease*. https://app.cochat.ai/papers/10.1172/jci104951
The paper
Kaplan, N. M., & Silah, J. G. (1964). The Effect of Angiotensin II on the Blood Pressure in Humans with Hypertensive Disease*. Journal of Clinical Investigation. https://doi.org/10.1172/jci104951

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.