The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The role of the liver in the metabolism of vitamin D
Open accessAbstract
The metabolism of vitamin D(3) has been studied after intravenous injection of 10 IU of [1,2-(3)H]-vitamin D(3) to vitamin D-deficient rats. The disappearance of the radioactivity from the plasma follows a very peculiar pattern characterized by an early rapid disappearance followed by a rebound of radioactivity before assuming still a third rather slow disappearance rate. The "rebound" phenomenon is concomitant with a rapid release of the radioactivity from the liver and is accounted for by the appearance of 25-hydroxycholecalciferol and other metabolites in the blood. It is postulated that the liver is the major site of transformation of vitamin D(3) into 25-hydroxycholecalciferol.
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Cites
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION
Bligh, E. G., & Dyer, W. J. (1959) · Canadian Journal of Biochemistry and Physiology · doi:10.1139/o59-099 · Cited by 54,751
Cited by
Cytochrome P450-mediated metabolism of vitamin D
Jones, G., Prosser, D. E., & Kaufmann, M. (2014) · Journal of Lipid Research · doi:10.1194/jlr.r031534 · Cited by 503
Fraser, D., Kooh, S. W., Kind, H. P., Holick, M. F., Tanaka, Y., & DeLuca, H. F. (1973) · New England Journal of Medicine · doi:10.1056/nejm197310182891601 · Cited by 426
Self-citationNew trends in encapsulation of liposoluble vitamins
Gonnet, M., Lethuaut, L., & Boury, F. (2010) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.01.037 · Cited by 334
Phenobarbital-Induced Alterations in Vitamin D Metabolism
Hahn, T. J., Birge, S. J., Scharp, C. R., & Avioli, L. V. (1972) · Journal of Clinical Investigation · doi:10.1172/jci106868 · Cited by 309
Metadata
- Authors
- Ponchon, G., & Deluca, H. F.
- Venue
- Journal of Clinical Investigation
- Published
- 1969-07-01
- Volume
- 48
- Issue
- 7
- Pages
- 1273-1279
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W2124792281
- Cited by
- 296
- References
- 1
- FWCI
- 40.86
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Ponchon, G., & Deluca, H. F. (1969). The role of the liver in the metabolism of vitamin D. Journal of Clinical Investigation. https://doi.org/10.1172/jci106093
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
