The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Iron deficiency in the rat. Physiological and biochemical studies of muscle dysfunction.
Open accessAbstract
Work performance on a treadmill has been evaluated in normal and iron-deficient rats. Anemia was removed as a variable by adjusting the hemoglobin of all animals to the same concentration. At a hemoglobin compatible with normal work performance, iron-deficient animals showed a marked impairment of running ability as compared to control animals. Iron therapy corrected the disability within 4 days. Concentrations of the cytochrome pigments and myoglobin, and rates of oxidative phosphorylation with pyruvate-malate, succinate, and alpha-glycerophosphate as substrates were all reduced in mitochondrial preparations from skeletal muscle of iron-deficient rats, but only the rate of phosphorylation with alpha-glycerophosphate as substrate increased significantly and in parallel with the recovery in work performance of the iron-deficient rats treated with iron dextran.
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Citations
Cites
RESPIRATORY ENZYMES IN OXIDATIVE PHOSPHORYLATION
Chance, B., & Williams, G. R. (1955) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)57189-7 · Cited by 1,473
Cited by
Haas, J. D., & Brownlie, T. (2001) · The Journal of Nutrition · doi:10.1093/jn/131.2.676s · Cited by 1,186
Iron deficiency and heart failure: diagnostic dilemmas and therapeutic perspectives
Jankowska, E. A., von Haehling, S., Anker, S. D., Macdougall, I. C., & Ponikowski, P. (2013) · European Heart Journal · doi:10.1093/eurheartj/ehs224 · Cited by 399
“The oxygen capacity is limited only with the most severe ID, when erythropoiesis is compromized with reduced haemoglobin.6 Iron deficiency and heart failure 823 In rodent studies, the distinctions between the effects of diminished oxygen transport and oxygen diffusion and decreased oxidative capacity (due to ID at the…”
BackgroundInfluentialIron Deficiency Predicts Impaired Exercise Capacity in Patients With Systolic Chronic Heart Failure
Jankowska, E. A., Rozentryt, P., Witkowska, A., Nowak, J., Hartmann, O., Ponikowska, B., Borodulin-Nadzieja, L., von Haehling, S., Doehner, W., Banasiak, W., et al. (2011) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2011.08.003 · Cited by 281
Oxidative stress and renal injury with intravenous iron in patients with chronic kidney disease
Agarwal, R., Vasavada, N., Sachs, N. G., & Chase, S. (2004) · Kidney International · doi:10.1111/j.1523-1755.2004.00648.x · Cited by 261
Iron supplementation improves endurance after training in iron-depleted, nonanemic women
Hinton, P. S., Giordano, C., Brownlie, T., & Haas, J. D. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.88.3.1103 · Cited by 228
Metadata
- Authors
- Finch, C. A., Miller, L. R., Inamdar, A. R., Person, R., Seiler, K., & Mackler, B.
- Venue
- Journal of Clinical Investigation
- Published
- 1976-08-01
- Volume
- 58
- Issue
- 2
- Pages
- 447-453
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W2092052199
- Cited by
- 307
- References
- 1
- FWCI
- 5.59
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
