The DOI matches its Crossref record.
Studies on the role of specific cell surface receptors in the removal of lipoprotein (a) in man.
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Multiple studies of LDLR in cells, animal models, and humans have provided inconsistent or conflicting results.
“Multiple studies of the LDL receptor (LDLR) in cells27-34, animal models25,32,35,36, and humans10,28,37-48 have provided inconsistent or conflicting results.”
From Functional interrogation of cellular Lp(a) uptake by genome-scale CRISPR screening (2025) · cites this paper as [28]
Multiple studies in cells have provided support for an interaction between Lp(a) and LDLR.
“Indeed, multiple studies in cells have provided support for an interaction between Lp(a) and LDLR27-30.”
From Functional interrogation of cellular Lp(a) uptake by genome-scale CRISPR screening (2025) · cites this paper as [28]
One study in humans found a defect in Lp(a) catabolism for patients with Familial Hypercholesterolemia.
“Likewise, while one study in humans found a defect in Lp(a) catabolism for patients with Familial Hypercholesterolemia (characterized by a defect in LDLR-mediated LDL uptake)28, other studies did not37-39.”
From Functional interrogation of cellular Lp(a) uptake by genome-scale CRISPR screening (2025) · cites this paper as [28]
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Research works printed but not linked: 6
- Kostner, G. M. 1976. Lp(a) lipoprotein and the genetic polymorphisms of lipoprotein B. In Low density lipo- proteins. C. E. Day and R. S. Levy, editors. Plenum Press, New York/London. 229-269.
- Brown, M. S., S. E. Dana, and J. L. Goldstein. 1973. Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in human fibroblasts by lipoproteins. Proc. Natl. Acad. Sci. USA. 70: 2162-2166.
- F. Krempler, G. M. Kostner, A. Roscher, F. Haslauer, K. Bolzano, and F. Sandhofer 33. Lee, D. M. 1976. Isolation and characterization of low density lipoproteins. In Low density lipoproteins. C. E. Day and R. S. Levy, editors. Plenum Press, New York/ London. 229-269.
- Snedecor, G. W., and W. C. Cochran. 1967. Statistical methods. The Iowa State University Press, Ames, Iowa.
- W. J. Dixon, editor. University of California Press, Berkely, Los Angeles, London.
- Brown, M. S., and J. L. Goldstein. 1974. Familial hy- percholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. Proc. Natl. Acad. Sci. USA. 71: 788-792.
Cited by
Sorted by citations
The mysteries of lipoprotein(a).
Utermann, G. (1989) · Science · doi:10.1126/science.2530631 · Cited by 1,257
Lipoprotein(a): resurrected by genetics
Kronenberg, F., & Utermann, G. (2013) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2012.02592.x · Cited by 521
Functional interrogation of cellular Lp(a) uptake by genome-scale CRISPR screening
Khan, T. G., Bragazzi Cunha, J., Raut, C., Burroughs, M., Vyas, H. S., Leix, K., Goonewardena, S. N., Smrcka, A. V., Speliotes, E. K., & Emmer, B. T. (2025) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2025.119174 · Cited by 6
Metadata
- Authors
- Krempler, F., Kostner, G. M., Roscher, A., Haslauer, F., Bolzano, K., & Sandhofer, F.
- Venue
- Journal of Clinical Investigation
- Published
- 1983-05-01
- Volume
- 71
- Issue
- 5
- Pages
- 1431-1441
- ISSN
- 0021-9738
- Cited by
- 157
- References
- 0
- Language
- en
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