The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Reinfection of liver graft by hepatitis C virus after liver transplantation.
Open accessAbstract
We have investigated hepatitis C virus (HCV) viremia before and after orthotopic liver transplantation (OLT). 38 patients were examined; 16 were anti-HCV positive and 22 anti-HCV negative pre-OLT in a RIBA-2 test (Ortho Diagnostic Systems Inc., Westwood, MA). HCV-RNA was detected using a modified nested polymerase chain reaction in 14/38 and 10/38 patients before and after OLT, respectively. 7 of these 14 subjects who were HCV-RNA positive before OLT were also positive for serum hepatitis B surface antigen. After OLT, six patients became HCV-RNA positive, likely as a result of transfusions, while four developed a probable recurrence of HCV infection. Infection of the liver graft by the same strain of HCV was indeed demonstrated by sequence analysis of a hypervariable domain (in the envelope region) in two cases. This establishes the possibility of HCV recurrence and shows the usefulness of polymerase chain reaction as the only assay currently capable of identifying HCV infection after OLT.
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Saiki, R. K., Scharf, S., Faloona, F., Mullis, K. B., Horn, G. T., Erlich, H. A., & Arnheim, N. (1985) · Science · doi:10.1126/science.2999980 · Cited by 8,956
Cited by
Quantitation of hepatitis C virus RNA in liver transplant recipients
Chazouilleres, O., Kim, M., Combs, C., Ferrell, L., Bacchetti, P., Roberts, J., Ascher, N. L., Neuwald, P., Wilber, J., Urdea, M., et al. (1994) · Gastroenterology · doi:10.1016/0016-5085(94)90759-5 · Cited by 277
Metadata
- Authors
- Féray, C., Samuel, D., Thiers, V, Gigou, M., Pichon, F., Bismuth, A., Reynes, M., Maisonneuve, P., Bismuth, H., & Bréchot, C.
- Venue
- Journal of Clinical Investigation
- Published
- 1992-04-01
- Volume
- 89
- Issue
- 4
- Pages
- 1361-1365
- ISSN
- 0021-9738 (ISSN-L)
- OpenAlex
- W2074530738
- Cited by
- 255
- References
- 1
- FWCI
- 19.30
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Reinfection of liver graft by hepatitis C virus after liver transplantation. https://app.cochat.ai/papers/10.1172/jci115723
- The paper
- Féray, C., Samuel, D., Thiers, V, Gigou, M., Pichon, F., Bismuth, A., Reynes, M., Maisonneuve, P., Bismuth, H., & Bréchot, C. (1992). Reinfection of liver graft by hepatitis C virus after liver transplantation. Journal of Clinical Investigation. https://doi.org/10.1172/jci115723
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
