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PSYCHIATRIC REACTION PATTERNS TO IMIPRAMINE
Abstract
1. One hundred and eighty voluntary inpatients (102 schizophrenic subjects, 67 subjects with affective disorders, and 11 "other" diagnoses) were studied during treatment with imipramine. 2. Seven imipramine induced behavioral reaction patterns and their relationships to diagnosis, age, sex, patterns of medication use, and hospital discharge evaluation are presented. These include mood elevation, explicit verbal denial, manic, reduction of episodic anxiety, agitated disorganization, anhedonic socialization, and non-response. 3. Imipramine was favorably evaluated in 79% of subjects with affective disorders and 51% of schizophrenic patients. 4. The use of psychiatric reaction patterns to psychotropic drugs for categorizing patients and providing a basis for a more rational pharmacotherapy are emphasized.
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Citations
Cited by
Chorpita, B. F., Yim, L., Moffitt, C., Umemoto, L. A., & Francis, S. E. (2000) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(99)00130-8 · Cited by 1,966
Chambless, D. L., Caputo, G. C., Bright, P., & Gallagher, R. (1984) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.52.6.1090 · Cited by 1,247
Quality of Life in Individuals With Anxiety Disorders
Mendlowicz, M. V., & Stein, M. B. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.5.669 · Cited by 955
Delineation of two drug-responsive anxiety syndromes
Klein, D. F. (1964) · Psychopharmacologia · doi:10.1007/bf02193476 · Cited by 898
Self-citationGoldstein, A. J., & Chambless, D. L. (1978) · Behavior Therapy · doi:10.1016/s0005-7894(78)80053-7 · Cited by 572
Metadata
- Authors
- KLEIN, D. F., & FINK, M.
- Venue
- American Journal of Psychiatry
- Published
- 1962-11
- Volume
- 119
- Issue
- 5
- Pages
- 432-438
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2176521126
- Cited by
- 416
- References
- 0
- FWCI
- 11.28
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: PSYCHIATRIC REACTION PATTERNS TO IMIPRAMINE. https://app.cochat.ai/papers/10.1176/ajp.119.5.432
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- KLEIN, D. F., & FINK, M. (1962). PSYCHIATRIC REACTION PATTERNS TO IMIPRAMINE. American Journal of Psychiatry. https://doi.org/10.1176/ajp.119.5.432
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
