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Reduced Monoamine Oxidase Activity in Blood Platelets from Bipolar Depressed Patients
Abstract
Cellular monoamine oxidase (MAO) activity measured in blood platelets is significantly (45 percent) lower in depressed patients with a history of mania (bipolar patients) than in nonbipolar depressed patients and normal controls of similar age and sex. This difference in MAO activity may be related to other biological and psychological characteristics of these patients that suggest that bipolar patients constitute a specific subgroup among patients with affective disorders.
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Citations
Cited by
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Sensation seeking and risky behavior
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Schalling, D., Åsberg, M., Edman, G., & Oreland, L. (1987) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1987.tb02881.x · Cited by 441
Another look at the monoamine oxidases and the monoamine oxidase inhibitor drugs
Neff, N. H., & Yang, H.-Y. T. (1974) · Life Sciences · doi:10.1016/0024-3205(74)90089-7 · Cited by 324
Sensation seeking and psychopathology
Zuckerman, M., & Neeb, M. (1979) · Psychiatry Research · doi:10.1016/0165-1781(79)90007-6 · Cited by 288
Metadata
- Authors
- MURPHY, D. L., & WEISS, R.
- Venue
- American Journal of Psychiatry
- Published
- 1972-05
- Volume
- 128
- Issue
- 11
- Pages
- 1351-1357
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2152677053
- Cited by
- 335
- References
- 0
- FWCI
- 41.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Reduced Monoamine Oxidase Activity in Blood Platelets from Bipolar Depressed Patients. https://app.cochat.ai/papers/10.1176/ajp.128.11.1351
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- MURPHY, D. L., & WEISS, R. (1972). Reduced Monoamine Oxidase Activity in Blood Platelets from Bipolar Depressed Patients. American Journal of Psychiatry. https://doi.org/10.1176/ajp.128.11.1351
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
