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Amphetamine Psychosis: A "Model" Schizophrenia Mediated by Catecholamines
Abstract
Because of its close clinical similarity to acute paranoid schizophrenia, amphetamine psychosis may serve as a useful experimental model for schizophrenia. Molecular and clinical studies suggest that both the schizophrenia-like symptoms of amphetamine psychosis and the specific ability of phenothiazines to relieve the symptoms of schizophrenia and amphetamine psychosis may be the result of interactions with dopamine systems in the brain. The author discusses some implications of the roles dopamine and norepinephrine may play in mediating some schizophrenic symptoms.
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Citations
Cited by
ROBINSON, T., & BECKER, J. (1986) · Brain Research · doi:10.1016/s0006-8993(86)80193-7 · Cited by 2,106
Grace, A. A. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90196-u · Cited by 1,831
Robinson, T. E., & Becker, J. B. (1986) · Brain Research Reviews · doi:10.1016/0165-0173(86)90002-0 · Cited by 1,796
The neuropsychology of schizophrenia
Gray, J. A., Feldon, J., Rawlins, J. N. P., Hemsley, D. R., & Smith, A. D. (1991) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00065055 · Cited by 1,350
D'Souza, D. C., Perry, E., MacDougall, L., Ammerman, Y., Cooper, T., Wu, Y.-T., Braley, G., Gueorguieva, R., & Krystal, J. H. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300496 · Cited by 1,024
Metadata
- Authors
- SNYDER, S. H.
- Venue
- American Journal of Psychiatry
- Published
- 1973-01
- Volume
- 130
- Issue
- 1
- Pages
- 61-67
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2015161406
- Cited by
- 587
- References
- 0
- FWCI
- 32.27
- Type
- journal article
- Language
- en
- Open access
- closed
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- SNYDER, S. H. (1973). Amphetamine Psychosis: A "Model" Schizophrenia Mediated by Catecholamines. American Journal of Psychiatry. https://doi.org/10.1176/ajp.130.1.61
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
