The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Psychiatric implications of basic and clinical studies with corticotropin-releasing factor
Abstract
Corticotropin-releasing factor (CRF) is a newly sequenced neuropeptide thought to be a principal stimulus to pituitary corticotropin (ACTH) secretion. Evidence obtained from laboratory animals and primates is reviewed which indicates that CRF not only stimulates the pituitary-adrenal axis but also influences several aspects of CNS function which may be of relevance to psychiatric illness. Clinically, experience in administering ovine CRF to more than 150 individuals shows that CRF can be helpful in resolving differential diagnostic dilemmas in patients with various disorders of the hypothalamic-pituitary-adrenal axis and in furthering an understanding of the pathophysiology of conditions such as Cushing's disease and depression.
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Citations
Cites
β-Endorphin and Adrenocorticotropin Are Selected Concomitantly by the Pituitary Gland
Guillemin, R., Vargo, T., Rossier, J., Minick, S., Ling, N., Rivier, C., Vale, W., & Bloom, F. (1977) · Science · doi:10.1126/science.197601 · Cited by 1,419
Cited by
Kirschbaum, C., Kudielka, B. M., Gaab, J., Schommer, N. C., & Hellhammer, D. H. (1999) · Psychosomatic Medicine · doi:10.1097/00006842-199903000-00006 · Cited by 1,890
The link between childhood trauma and depression: insights from HPA axis studies in humans
Heim, C., Newport, D. J., Mletzko, T., Miller, A. H., & Nemeroff, C. B. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2008.03.008 · Cited by 1,704
Sex differences in HPA axis responses to stress: a review
Kudielka, B. M., & Kirschbaum, C. (2005) · Biological Psychology · doi:10.1016/j.biopsycho.2004.11.009 · Cited by 1,624
Nemeroff, C. B., Widerlöv, E., Bissette, G., Walléus, H., Karlsson, I., Eklund, K., Kilts, C. D., Loosen, P. T., & Vale, W. (1984) · Science · doi:10.1126/science.6334362 · Cited by 1,485
Sheline, Y. I., Sanghavi, M., Mintun, M. A., & Gado, M. H. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-12-05034.1999 · Cited by 1,382
“…relative contributions of adrenal hypersensitivity to ACTH (Amsterdam et al., 1989), pituitary resistance to GC feedback (Holsboer et al., 1987), pituitary hypersensitivity to CRF and other hormones (Gold et al., 1984), and resistance at the hippocampus (Sapolsky et al., 1991; Young et al., 1991).”
Background
Metadata
- Venue
- American Journal of Psychiatry
- Published
- 1984-05-01
- Volume
- 141
- Issue
- 5
- Pages
- 619-627
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2400730498
- Cited by
- 481
- References
- 1
- FWCI
- 12.57
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Psychiatric implications of basic and clinical studies with corticotropin-releasing factor. https://app.cochat.ai/papers/10.1176/ajp.141.5.619
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- Psychiatric implications of basic and clinical studies with corticotropin-releasing factor. (1984). American Journal of Psychiatry. https://doi.org/10.1176/ajp.141.5.619
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
