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A family study of generalized anxiety disorder
Abstract
The frequency of generalized anxiety disorder was higher among first-degree relatives of probands with generalized anxiety (N = 20) than among the relatives of control subjects (N = 20), but it was not higher among relatives of probands with panic disorder (N = 40) or agoraphobia (N = 40). Also, the frequency of panic disorder was higher among relatives of probands with panic disorder than among control relatives but was not higher among relatives of generalized anxiety probands. Relatives of probands with generalized anxiety who had the same disorder had a mild, stress-related illness. The results confirm the separation between generalized anxiety disorder and panic disorder but challenge the distinction between generalized anxiety and adjustment disorders.
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Citations
Cited by
A Review and Meta-Analysis of the Genetic Epidemiology of Anxiety Disorders
Hettema, J. M., Neale, M. C., & Kendler, K. S. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.10.1568 · Cited by 1,563
Major Depression and Generalized Anxiety Disorder: Same Genes, (Partly) Different Environments?
Kendler, K. S. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820090044008 · Cited by 773
Bienvenu, O. J., Samuels, J. F., Wuyek, L. A., Liang, K.-Y., Wang, Y., Grados, M. A., Cullen, B. A., Riddle, M. A., Greenberg, B. D., Rasmussen, S. A., et al. (2012) · Psychological Medicine · doi:10.1017/s0033291711000742 · Cited by 286
Vulnerability factors among children at risk for anxiety disorders
Merikangas, K. R., Avenevoli, S., Dierker, L., & Grillon, C. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00172-9 · Cited by 229
Should OCD be classified as an anxiety disorder in DSM-V?
Stein, D. J., Fineberg, N. A., Bienvenu, O. J., Denys, D., Lochner, C., Nestadt, G., Leckman, J. F., Rauch, S. L., & Phillips, K. A. (2010) · Depression and Anxiety · doi:10.1002/da.20699 · Cited by 212
Metadata
- Venue
- American Journal of Psychiatry
- Published
- 1987-08-01
- Volume
- 144
- Issue
- 8
- Pages
- 1019-1024
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2419345341
- Cited by
- 173
- References
- 0
- FWCI
- 8.02
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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