The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Schizophrenia and the parvalbumin-containing class of cortical local circuit neurons
Abstract
OBJECTIVE: The purpose of this study was to test the hypothesis that abnormalities in the parvalbumin-containing subclass of local circuit neurons contribute to altered gamma-aminobutyric acid (GABA) neurotransmission in the prefrontal cortex of schizophrenic subjects. METHOD: Profile counts and somal size measures were made of parvalbumin-immunoreactive neurons in areas 9, 46, and 17 from 15 matched pairs of schizophrenic and normal comparison subjects. RESULTS: No differences in relative density, laminar distribution, or somal size of labeled neurons were found in any region. CONCLUSIONS: These findings suggest that altered GABA neurotransmission in schizophrenia is due to either abnormalities in other sub-populations of prefrontal cortical GABA neurons or abnormalities in the parvalbumin-containing subclass that could not be detected in the present study.
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Hayes, T. L., & Lewis, D. A. (1992) · Cerebral Cortex · doi:10.1093/cercor/2.1.56 · Cited by 80
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Cited by
Cortical inhibitory neurons and schizophrenia
Lewis, D. A., Hashimoto, T., & Volk, D. W. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1648 · Cited by 2,297
Self-citationAbnormal neural oscillations and synchrony in schizophrenia
Uhlhaas, P. J., & Singer, W. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2774 · Cited by 2,120
GABAergic Interneurons Implications for Understanding Schizophrenia and Bipolar Disorder
Benes, F. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00225-1 · Cited by 1,082
Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia
Lewis, D. A., Curley, A. A., Glausier, J. R., & Volk, D. W. (2012) · Trends in Neurosciences · doi:10.1016/j.tins.2011.10.004 · Cited by 1,071
Self-citationLisman, J. E., Coyle, J. T., Green, R. W., Javitt, D. C., Benes, F. M., Heckers, S., & Grace, A. A. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2008.02.005 · Cited by 1,010
Metadata
- Venue
- American Journal of Psychiatry
- Published
- 1997-07-01
- Volume
- 154
- Issue
- 7
- Pages
- 1013-1015
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W1211088797
- Cited by
- 191
- References
- 1
- FWCI
- 5.98
- Type
- journal article
- Language
- en
- Open access
- closed
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- Schizophrenia and the parvalbumin-containing class of cortical local circuit neurons. (1997). American Journal of Psychiatry. https://doi.org/10.1176/ajp.154.7.1013
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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