Development and validation of a screening instrument for bipolar spectrum disorder: the Mood Disorder Questionnaire
Abstract
OBJECTIVE: Bipolar spectrum disorders, which include bipolar I, bipolar II, and bipolar disorder not otherwise specified, frequently go unrecognized, undiagnosed, and untreated. This report describes the validation of a new brief self-report screening instrument for bipolar spectrum disorders called the Mood Disorder Questionnaire. METHOD: A total of 198 patients attending five outpatient clinics that primarily treat patients with mood disorders completed the Mood Disorder Questionnaire. A research professional, blind to the Mood Disorder Questionnaire results, conducted a telephone research diagnostic interview by means of the bipolar module of the Structured Clinical Interview for DSM-IV. RESULTS: A Mood Disorder Questionnaire screening score of 7 or more items yielded good sensitivity (0.73) and very good specificity (0.90). CONCLUSIONS: The Mood Disorder Questionnaire is a useful screening instrument for bipolar spectrum disorder in a psychiatric outpatient population.
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The Mood Disorders Questionnaire is one of the few screening tools for bipolar disorder and the most commonly used.
“One of the few screening measures for bipolar disorder, and the most commonly used, is the Mood Disorders Questionnaire (MDQ) [38].”
From Perinatal mental illness: Definition, description and aetiology (2014) · cites this paper as [38]
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References 7 · Cited by 1,525
- Authors
- Hirschfeld, R. M. A., Williams, J. B. W., Spitzer, R. L., Calabrese, J. R., Flynn, L., Keck, P. E., Lewis, L., McElroy, S. L., Post, R. M., Rapport, D. J., Russell, J. M., Sachs, G. S., & Zajecka, J.
- Affiliations
- The University of Texas Medical Branch at Galveston (US)
- ORCID
- Venue
- American Journal of Psychiatry
- Published
- 2000-11-01
- Volume
- 157
- Issue
- 11
- Pages
- 1873-1875
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2143002682
- Cited by
- 1,525
- References
- 7
- Citations by year
- 2026: 62 · 2025: 73 · 2024: 73 · 2023: 69 · 2022: 78 · 2021: 55 · 2020: 74 · 2019: 61 · 2018: 67 · 2017: 59 · 2016: 71 · 2015: 90 · 2014: 80 · 2013: 79 · 2012: 71
- FWCI
- 10.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- bipolar spectrum disorders, Mood Disorder Questionnaire, screening tool, self-report questionnaire, bipolar I disorder, bipolar II disorder, bipolar disorder not otherwise specified, sensitivity and specificity
- MeSH terms
- Adolescent, Adult, Aged, Ambulatory Care, Bipolar Disorder, Female, Humans, Male, Middle Aged, Personality Inventory, Psychiatric Status Rating Scales, Psychometrics, Surveys and Questionnaires, Sensitivity and Specificity, Telephone, Reproducibility of Results
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