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The Psychiatric Symptoms of Rheumatic Fever
Open accessAbstract
OBJECTIVE: This study examined the frequency and age at onset of psychiatric disorders among children with rheumatic fever, Sydenham's chorea, or both and a comparison group. METHOD: Twenty children with rheumatic fever, 22 with Sydenham's chorea, and 20 comparison children were assessed by means of a semistructured interview and rating scales for tic disorders and obsessive-compulsive disorder. RESULTS: Obsessive-compulsive symptoms were more frequent in both the Sydenham's chorea and rheumatic fever groups than in the comparison group. The Sydenham's chorea group had a higher frequency of major depressive disorder, tic disorders, and attention deficit hyperactivity disorder (ADHD) than both the comparison and rheumatic fever groups. ADHD symptoms were associated with a higher risk of developing Sydenham's chorea. CONCLUSIONS: Both the rheumatic fever and Sydenham's chorea groups were associated with a higher risk of developing neuropsychiatric disorders than the comparison group. ADHD appears to be a risk factor for Sydenham's chorea in children with rheumatic fever.
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Citations
Cited by
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Obsessive-compulsive disorder phenotypes: implications for genetic studies
Miguel, E. C., Leckman, J. F., Rauch, S., do Rosario-Campos, M. C., Hounie, A. G., Mercadante, M. T., Chacon, P., & Pauls, D. L. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001617 · Cited by 282
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Hanson, D. R., & Gottesman, I. I. (2005) · BMC Medical Genetics · doi:10.1186/1471-2350-6-7 · Cited by 276
Brander, G., Pérez-Vigil, A., Larsson, H., & Mataix-Cols, D. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.03.011 · Cited by 172
Ferrão, Y. A., Miguel, E., & Stein, D. J. (2009) · Psychiatry Research · doi:10.1016/j.psychres.2008.06.008 · Cited by 107
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Metadata
- Authors
- Mercadante, M. T., Busatto, G. F., Lombroso, P. J., Prado, L., Rosário-Campos, M. C., do Valle, R., Marques-Dias, M. J., Kiss, M. H., Leckman, J. F., & Miguel, E. C.
- Venue
- American Journal of Psychiatry
- Published
- 2000-12-01
- Volume
- 157
- Issue
- 12
- Pages
- 2036-2038
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2017985363
- Cited by
- 159
- References
- 0
- FWCI
- 7.13
- Type
- journal article
- Language
- en
- Open access
- green
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- Mercadante, M. T., Busatto, G. F., Lombroso, P. J., Prado, L., Rosário-Campos, M. C., do Valle, R., Marques-Dias, M. J., Kiss, M. H., Leckman, J. F., & Miguel, E. C. (2000). The Psychiatric Symptoms of Rheumatic Fever. American Journal of Psychiatry. https://doi.org/10.1176/appi.ajp.157.12.2036
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