The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Meta-Analysis of the Association Between the 7-Repeat Allele of the Dopamine D4 Receptor Gene and Attention Deficit Hyperactivity Disorder
Open accessAbstract
OBJECTIVE: Family, twin, and adoption studies show attention deficit hyperactivity disorder (ADHD) to have a substantial genetic component. Although several studies have shown an association between ADHD and the 7-repeat allele of the dopamine D(4) receptor gene (DRD4), several studies have not. Thus, the status of the ADHD-DRD4 association is uncertain. METHOD: Meta-analysis was applied to case-control and family-based studies of the association between ADHD and DRD4 to assess the joint evidence for the association, the influence of individual studies, and evidence for publication bias. RESULTS: For both the case-control and family-based studies, the authors found 1) support for the association between ADHD and DRD4, 2) no evidence that this association was accounted for by any one study, and 3) no evidence for publication bias. CONCLUSIONS: Although the association between ADHD and DRD4 is small, these results suggest that it is real. Further studies are needed to clarify what variant of DRD4 (or some nearby gene) accounts for this association.
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Cites
Multiple dopamine D4 receptor variants in the human population
Tol, H. H. M. V., Wu, C. M., Guan, H.-C., Ohara, K., Bunzow, J. R., Civelli, O., Kennedy, J., Seeman, P., Niznik, H. B., & Jovanovic, V. (1992) · Nature · doi:10.1038/358149a0 · Cited by 955
Modulation of intracellular cyclic AMP levels by different human dopamine D4 receptor variants
Asghari, V., Sanyal, S., Buchwaldt, S., Paterson, A., Jovanovic, V., & Van Tol, H. H. M. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.65031157.x · Cited by 858
Meta‐analysis for 2 × 2 tables: A bayesian approach
Carlin, J. B. (1992) · Statistics in Medicine · doi:10.1002/sim.4780110202 · Cited by 164
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Molecular genetics of attention-deficit/hyperactivity disorder
Faraone, S. V., Perlis, R. H., Doyle, A. E., Smoller, J. W., Goralnick, J. J., Holmgren, M. A., & Sklar, P. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.11.024 · Cited by 2,357
Self-citationNeuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes
Castellanos, F. X., & Tannock, R. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn896 · Cited by 1,827
The genetics of addictions: uncovering the genes
Goldman, D., Oroszi, G., & Ducci, F. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1635 · Cited by 1,099
sagvolden, T., johansen, E. B., aase, H., & russell, V. A. (2005) · Behavioral and Brain Sciences · doi:10.1017/s0140525x05000075 · Cited by 1,035
Metadata
- Authors
- Faraone, S. V., Doyle, A. E., Mick, E., & Biederman, J.
- Venue
- American Journal of Psychiatry
- Published
- 2001-07-01
- Volume
- 158
- Issue
- 7
- Pages
- 1052-1057
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2126701473
- Cited by
- 753
- References
- 3
- FWCI
- 9.30
- Type
- journal article
- Language
- en
- Open access
- green
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- Faraone, S. V., Doyle, A. E., Mick, E., & Biederman, J. (2001). Meta-Analysis of the Association Between the 7-Repeat Allele of the Dopamine D4 Receptor Gene and Attention Deficit Hyperactivity Disorder. American Journal of Psychiatry. https://doi.org/10.1176/appi.ajp.158.7.1052
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