The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Age at Onset in Bipolar I Affective Disorder: Further Evidence for Three Subgroups
Abstract
OBJECTIVE: Preliminary data suggested that there are three subgroups of bipolar affective disorder based on age at onset. The authors sought to replicate those findings and determine the cut-off age of each subgroup. METHOD: Admixture analysis was used to determine the best-fitting model for the observed ages at onset of 368 consecutively admitted patients. The results obtained were compared with those of the previously described model. The authors also investigated whether affected siblings are more likely to belong to the same theoretical age-at-onset subgroup as identified by admixture analysis. RESULTS: The existence of three subgroups defined by age at onset was confirmed. The mean ages estimated in this model were 17.4 years (SD=2.3), 25.1 years (SD=6.2), and 40.4 years (SD=11.3). Affected siblings were more likely to belong to the same theoretical subgroup. CONCLUSIONS: There are three age-at-onset subgroups of bipolar patients, and specific familial vulnerability factors might underlie each subgroup.
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Cites
Familial influences on the clinical characteristics of major depression: a twin study
Kendler, K. S., Neale, M. C., Kessler, R. C., Heath, A. C., & Eaves, L. J. (1992) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1992.tb03283.x · Cited by 59
Cited by
Sleep and circadian rhythm disruption in psychiatric and neurodegenerative disease
Wulff, K., Gatti, S., Wettstein, J. G., & Foster, R. G. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2868 · Cited by 1,055
Perlis, R. H., Miyahara, S., Marangell, L. B., Wisniewski, S. R., Ostacher, M., DelBello, M. P., Bowden, C. L., Sachs, G. S., & Nierenberg, A. A. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.01.022 · Cited by 852
Manchia, M., Adli, M., Akula, N., Ardau, R., Aubry, J.-M., Backlund, L., Banzato, C. E., Baune, B. T., Bellivier, F., Bengesser, S., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065636 · Cited by 417
Self-citationEarly Intervention in Bipolar Disorder
Vieta, E., Salagre, E., Grande, I., Carvalho, A. F., Fernandes, B. S., Berk, M., Birmaher, B., Tohen, M., & Suppes, T. (2018) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2017.17090972 · Cited by 354
Sajatovic, M., Strejilevich, S. A., Gildengers, A. G., Dols, A., Al Jurdi, R. K., Forester, B. P., Kessing, L. V., Beyer, J., Manes, F., Rej, S., et al. (2015) · Bipolar Disorders · doi:10.1111/bdi.12331 · Cited by 309
Metadata
- Authors
- Bellivier, F., Golmard, J.-L., Rietschel, M., Schulze, T. G., Malafosse, A., Preisig, M., McKeon, P., Mynett-Johnson, L., Henry, C., & Leboyer, M.
- Venue
- American Journal of Psychiatry
- Published
- 2003-05-01
- Volume
- 160
- Issue
- 5
- Pages
- 999-1001
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2135071346
- Cited by
- 237
- References
- 1
- FWCI
- 5.45
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bellivier, F., Golmard, J.-L., Rietschel, M., Schulze, T. G., Malafosse, A., Preisig, M., McKeon, P., Mynett-Johnson, L., Henry, C., & Leboyer, M. (2003). Age at Onset in Bipolar I Affective Disorder: Further Evidence for Three Subgroups. American Journal of Psychiatry. https://doi.org/10.1176/appi.ajp.160.5.999
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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