Early-Life Environmental Factors Impacting the Development of Psychopathology
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Early life stress increases the likelihood of developing depression, suicidal behavior, and various other psychiatric disorders during adulthood.
“Experiencing stress in the early life, commonly known as Early life stress (ELS), increases the likelihood of developing depression, suicidal behavior, and various other psychiatric disorders during adulthood.26,197–200”
From Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential (2023) · cites this paper as [198]
Cites
Blackburn, E. H., Epel, E. S., & Lin, J. (2015) · Science · doi:10.1126/science.aab3389 · Cited by 1,596 · see citing works
Prenatal Infection and Schizophrenia: A Review of Epidemiologic and Translational Studies
Brown, A. S., & Derkits, E. J. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.09030361 · Cited by 1,269 · see citing works
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Yuan, M., Yang, B., Rothschild, G., Mann, J. J., Sanford, L. D., Tang, X., Huang, C., Wang, C., & Zhang, W. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01519-z · Cited by 246 · see citing works
- Authors
- Kalin, N. H.
- Affiliations
- University of Wisconsin–Madison (US)
- Corresponding author
- Kalin, Ned H.
- ORCID
- Kalin, Ned H.
- Venue
- American Journal of Psychiatry
- Published
- 2020-01-01
- Volume
- 177
- Issue
- 1
- Pages
- 1-3
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2998515740
- Cited by
- 9
- References
- 2
- Citations by year
- 2025: 2 · 2023: 2 · 2022: 2 · 2020: 3
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- psychopathology, developmental origins of mental disorders, childhood adversity, mental health development
- MeSH terms
- Humans, Psychopathology, Risk Factors, Gene-Environment Interaction
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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