The DOI matches its OpenAlex record; 86 of the 86 references it cites were found in a registry or an index.
Prevalence, Clinical Manifestations, Etiology, and Treatment of Depression in Parkinson's Disease
Abstract
To determine the extent to which depression complicates Parkinson's disease (PD), the authors analyzed the literature on depression in PD in order to report on its prevalence, clinical manifestations, and treatment. By means of MEDLINE literature searches, the analysis focused on 45 PD depression studies conducted from 1922 through 1998. The results indicate that the prevalence of depression is 31% for all PD patients. The clinical manifestations of PD depression include apathy, psychomotor retardation, memory impairment, pessimism, irrationality, and suicidal ideation without suicidal behavior. PD depression is effectively treated with a variety of antidepressants, most commonly at present the selective serotonin reuptake inhibitors. Anecdotal evidence supports the use of sertraline to treat PD depression.
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Citations
Cites
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Depression, intellectual impairment, and Parkinson disease
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The Neuropathologic Basis of Different Clinical Subgroups of Parkinson's Disease
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Cited by
A systematic review of prevalence studies of depression in Parkinson's disease
Reijnders, J. S. A. M., Ehrt, U., Weber, W. E. J., Aarsland, D., & Leentjens, A. F. G. (2008) · Movement Disorders · doi:10.1002/mds.21803 · Cited by 1,239
Chaudhuri, K. R., Martinez‐Martin, P., Schapira, A. H. V., Stocchi, F., Sethi, K., Odin, P., Brown, R. G., Koller, W., Barone, P., MacPhee, G., et al. (2006) · Movement Disorders · doi:10.1002/mds.20844 · Cited by 1,100
Koolschijn, P. C. M. P., van Haren, N. E. M., Lensvelt‐Mulders, G. J. L. M., Hulshoff Pol, H. E., & Kahn, R. S. (2009) · Human Brain Mapping · doi:10.1002/hbm.20801 · Cited by 902
Hirschfeld, R. M. A. (2001) · The Primary Care Companion For CNS Disorders · doi:10.4088/pcc.v03n0609 · Cited by 661
Effect of Psychiatric and Other Nonmotor Symptoms on Disability in Parkinson's Disease
Weintraub, D., Moberg, P. J., Duda, J. E., Katz, I. R., & Stern, M. B. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52219.x · Cited by 381
Metadata
- Authors
- Slaughter, J. R., Slaughter, K. A., Nichols, D., Holmes, S. E., & Martens, M. P.
- Venue
- Journal of Neuropsychiatry
- Publisher
- American Psychiatric Association Publishing
- Published
- 2001-05-01
- Volume
- 13
- Issue
- 2
- Pages
- 187-196
- ISSN
- 0895-0172 (ISSN-L)
- OpenAlex
- W2152289942
- Cited by
- 284
- References
- 86
- FWCI
- 6.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Prevalence, Clinical Manifestations, Etiology, and Treatment of Depression in Parkinson's Disease. https://app.cochat.ai/papers/10.1176/appi.neuropsych.13.2.187
- The paper
- Slaughter, J. R., Slaughter, K. A., Nichols, D., Holmes, S. E., & Martens, M. P. (2001). Prevalence, Clinical Manifestations, Etiology, and Treatment of Depression in Parkinson's Disease. Journal of Neuropsychiatry. https://doi.org/10.1176/appi.neuropsych.13.2.187
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
