Cited by 182Systemic Lupus Erythematosus ResearchCardiovascular Function and Risk FactorsVasculitis and related conditions

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Cardiovascular Manifestations in Systemic Lupus Erythematosus. Prospective Study of 100 Patients

Badui, Elias, Garcia-Rubi, David, Robles, Elsa, Jimenez, Javier, Juan, Lourdes, Deleze, Margarita, Diaz, Arturo, Mintz, Gregorio·1985·Angiology

Abstract

One hundred consecutive female patients with active systemic lupus erythe matosus (SLE) were studied from the cardiovascular point of view by means of non invasive methods. Seventy percent of the cases presented some type of car diovascular anomaly. Seventy four percent of the resting electrocardiograms were abnormal as well as 72% of the M mode echocardiograms and 55% of the cardiac X ray series. The most frequent observed complications were: pericar ditis and or pericardial effusion (39%), arterial hypertension (22%), ischemic heart disease (16%), myocarditis (14%), congestive heart failure (10%), pulmo nary hypertension (9%), valvular heart disease (9%), pleural effusion (7%) and cerebro vascular accident (3%). We analized each one of these complications and found of special interest the high incidence of ischemic heart disease which is more frequent than has been hitherto reported. Ischemic heart disease was observed in two types of patients: a) Those with long term steroid therapy. In these, the mechanism seems to be an atherosclerotic disease probably induced by the chronic use of steroids. The management of these cases do not differ from other types of coronary heart disease due to atherosclerosis. b) Those with frank episodes of vasculitis in whom the basic mechanism is an inflammatory process of the coronary arteries and its treatment is fundamentally that of the vasculitis. We consider necessary to study routinely all patients with SLE through non invasive cardiological methods.

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Metadata

Authors
Badui, E., Garcia-Rubi, D., Robles, E., Jimenez, J., Juan, L., Deleze, M., Diaz, A., & Mintz, G.
Affiliations
  • From the Cardiology Service of the General Hospital, National Medical Center, Mexican Institute of Social Security, Mexico City, Mexico
  • Mexican Social Security Institute (MX)
  • From the Rheumatology Service of the General Hospital, National Medical Center, Mexican Institute of Social Security, Mexico City, Mexico
Venue
Angiology
Published
1985-07
Volume
36
Issue
7
Pages
431-441
ISSN
  • 0003-3197 (ISSN-L)
  • 1940-1574
OpenAlex
W2057653821
Cited by
182
References
0
Citations by year
2026: 2 · 2025: 1 · 2024: 4 · 2023: 2 · 2022: 5 · 2021: 2 · 2020: 7 · 2019: 5 · 2018: 1 · 2017: 6 · 2016: 2 · 2015: 3 · 2014: 5 · 2013: 9 · 2012: 5
FWCI
1.59
Type
journal article
Language
en
Open access
closed
Locations
  • Angiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Rheumatology › Systemic Lupus Erythematosus Research
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
  • Health Sciences › Medicine › Rheumatology › Vasculitis and related conditions
Keywords
systemic lupus erythematosus, cardiovascular manifestations, ischemic heart disease, pericarditis, pericardial effusion, myocarditis, congestive heart failure, pulmonary hypertension, valvular heart disease, hypertension, vasculitis, atherosclerosis, electrocardiographic abnormalities, echocardiography
MeSH terms
Adolescent, Adult, Cardiovascular Diseases, Coronary Disease, Echocardiography, Electrocardiography, Female, Heart Failure, Humans, Hypertension, Hypertension, Pulmonary, Lupus Erythematosus, Systemic, Middle Aged, Myocarditis, Pericarditis, Prospective Studies, Radiography, Steroids

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