Computer models for metabolic studies on plasma proteins
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Claims the paper makes
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Inflammation increases escape of serum albumin from plasma.
“Inflammation increases capillary permeability and escape of serum albumin, leading to expansion of interstitial space and increasing the distribution volume of albumin.”
From Hypoalbuminemia: Pathogenesis and Clinical Significance (2019) · cites this paper as [17]
Other sites, including muscle and adipose tissue in collaboration with the liver and possibly the kidney, release solutes into the vascular compartment from where they enter the interstitium at increased rates, facilitated by increased capillary permeability.
“Other sites (muscle and adipose tissue in collaboration with the liver and, possibly, the kidney12) release these solutes into the vascular compartment from where they enter the extravascular extracellular compartment (interstitium) at increased rates, also facilitated by the increased capillary permeability.4, 13, 14, 15, 16, 17”
From Hypoalbuminemia: Pathogenesis and Clinical Significance (2019) · cites this paper as [17]
Cites
The Biology of Human Starvation: Volume I
KEYS, A., BROŽEK, J., HENSCHEL, A., MICKELSEN, O., & TAYLOR, H. L. (1950) · doi:10.5749/j.ctv9b2tqv · Cited by 2,039 · see citing works
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Hypoalbuminemia: Pathogenesis and Clinical Significance
Soeters, P. B., Wolfe, R. R., & Shenkin, A. (2019) · Journal of Parenteral and Enteral Nutrition · doi:10.1002/jpen.1451 · Cited by 1,448 · see citing works
INCREASED VASCULAR PERMEABILITY: A MAJOR CAUSE OF HYPOALBUMINAEMIA IN DISEASE AND INJURY
Fleck, A., Hawker, F., Wallace, P. I., Raines, G., Trotter, J., Ledingham, I. M., & Calman, K. C. (1985) · The Lancet · doi:10.1016/s0140-6736(85)91447-3 · Cited by 898 · see citing works
Self-citation
- Authors
- Fleck, A.
- Affiliations
- University of London (GB)
- Corresponding author
- Fleck, A
- Venue
- Annals of Clinical Biochemistry: International Journal of Laboratory Medicine
- Publisher
- SAGE Publications
- Published
- 1985-01
- Volume
- 22
- Issue
- 1
- Pages
- 33-49
- ISSN
- 0004-5632 (ISSN-L)
- 1758-1001
- OpenAlex
- W2316443608
- Cited by
- 34
- References
- 1
- Citations by year
- 2021: 1 · 2018: 1 · 2015: 1
- FWCI
- 1.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Clinical Biochemistry International Journal of Laboratory Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Interaction Studies and Fluorescence Analysis
- Health Sciences › Medicine › Physiology › Clinical Laboratory Practices and Quality Control
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Structure and Dynamics
- Keywords
- plasma proteins, computer model, metabolic modeling, protein metabolism
- MeSH terms
- Blood Proteins, Capillary Permeability, Computers, Half-Life, Humans, Lymph, Mathematics, Models, Biological, Plasma Volume, Reference Values, Serum Albumin
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