The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
A Pilot Study of Methyiphenidate, Clonidine, or the Combination in ADHD Comorbid with Aggressive Oppositional Defiant or Conduct Disorder
Abstract
A pilot comparison of the safety and efficacy of methylphenidate (MPH) combined with clonidine, clonidine monotherapy, or MPH monotherapy in 6to 16-year-old children diagnosed with attention deficit hyperactivity disorder (ADHD) and comorbid aggressive oppositional defiant disorder or conduct disorder was completed. Study design was a 3-month, randomized, blinded, group comparison with eight subjects per group. No placebo comparison was used. All three treatment groups showed significant improvements in attention deficits, impulsivity, oppositional, and conduct disordered symptoms as assessed by parent and teacher rating scales and laboratory measures. Significant differences among treatment groups were found only on a few measures. Only the clonidine monotherapy group showed significantly decreased fine motor speed. These results suggest the safety and efficacy of clonidine alone or in combination with MPH for the treatment of ADHD and aggressive oppositional and conduct disorders.
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Citations
Cites
Clonidine in Child and Adolescent Psychiatry
HUNT, R. D., CAPPER, L., & O'CONNELL, P. (1990) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.1990.1.87 · Cited by 127
Cited by
Scahill, L., Chappell, P. B., Kim, Y. S., Schultz, R. T., Katsovich, L., Shepherd, E., Arnsten, A. F. T., Cohen, D. J., & Leckman, J. F. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.7.1067 · Cited by 588
Catalá-López, F., Hutton, B., Núñez-Beltrán, A., Page, M. J., Ridao, M., Macías Saint-Gerons, D., Catalá, M. A., Tabarés-Seisdedos, R., & Moher, D. (2017) · PLOS ONE · doi:10.1371/journal.pone.0180355 · Cited by 396
Methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD)
Storebø, O. J., Ramstad, E., Krogh, H. B., Nilausen, T. D., Skoog, M., Holmskov, M., Rosendal, S., Groth, C., Magnusson, F. L., Moreira-Maia, C. R., et al. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd009885.pub2 · Cited by 347
Biederman, J., Melmed, R. D., Patel, A., McBurnett, K., Konow, J., Lyne, A., Scherer, N., & for the SPD503 Study Group (2008) · Pediatrics · doi:10.1542/peds.2006-3695 · Cited by 317
Sallee, F. R., Lyne, A., Wigal, T., & McGough, J. J. (2009) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2008.0080 · Cited by 306
Metadata
- Authors
- Connor, D. F., Barkley, R. A., & Davis, H. T.
- Venue
- Clinical Pediatrics
- Publisher
- SAGE Publications
- Published
- 2000-01
- Volume
- 39
- Issue
- 1
- Pages
- 15-25
- ISSN
- 0009-9228 (ISSN-L)
- 1938-2707
- OpenAlex
- W2109935740
- Cited by
- 203
- References
- 1
- FWCI
- 7.13
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: A Pilot Study of Methyiphenidate, Clonidine, or the Combination in ADHD Comorbid with Aggressive Oppositional Defiant or Conduct Disorder. https://app.cochat.ai/papers/10.1177/000992280003900102
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- Connor, D. F., Barkley, R. A., & Davis, H. T. (2000). A Pilot Study of Methyiphenidate, Clonidine, or the Combination in ADHD Comorbid with Aggressive Oppositional Defiant or Conduct Disorder. Clinical Pediatrics. https://doi.org/10.1177/000992280003900102
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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