Randomized Controlled Evaluation of Non-surgical Treatments for Temporomandibular Joint Anterior Disk Displacement without Reduction
Abstract
The common methods for treating anterior disk displacement without reduction (ADDwor) are not based on randomized controlled clinical trials. Our study evaluated non-surgical treatments in 69 MRI-confirmed ADDwor subjects (m/f = 6/63). Subjects were randomly assigned to a control group and one of two treatment groups. Outcomes included maximum mouth opening, visual analogue scale of pain, and daily activity limitation. Calibrated examiners collected data at the initial interview and at 0, 2, 4, and 8 weeks of treatment. At the eight-week point, within-group improvements were present for all variables, for all groups. Between-group differences were not highly evident, with only mean daily activity limitation for the self-care/NSAID group being significantly lower than that of the occlusal appliance/jaw mobilization + self-care/NSAID group at the two- and four-week time-points. These results suggest that ADDwor subjects will improve with only minimal treatment intervention, and no significant difference was evident for the treatments tested and the control condition.
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In general, MT plus exercises reduced symptoms and increased ROM for patients with arthrogenous TMD, particularly for those with reduced ROM due to disk displacements without reduction (closed lock).
“In general, we found that MT plus exercises reduced symptoms and increased ROM for patients with arthrogenous TMD, particularly for those with reduced ROM due to disk displacements without reduction (”
From Effectiveness of Manual Therapy and Therapeutic Exercise for Temporomandibular Disorders: Systematic Review and Meta-Analysis (2016) · cites this paper as [90]
When pooling results from studies with homogeneous interventions and similar outcomes, diagnoses, and available data, pain was significantly reduced in patients receiving MT combined with exercises compared with splint therapy, self-care, or medications.
“When pooling the results from the studies with homogeneous interventions and similar outcomes, diagnoses, and available data, 69,78,87,88,90 we found that pain was significantly reduced in patients receiving MT combined with exercises compared with splint therapy, self-care, or medications.”
From Effectiveness of Manual Therapy and Therapeutic Exercise for Temporomandibular Disorders: Systematic Review and Meta-Analysis (2016) · cites this paper as [90]
When looking at active mouth opening, MT plus exercises significantly increased active mouth opening compared with splint therapy, self-care, or medications.
“When looking at active mouth opening, 69,87,88,90 we found that MT plus exercises significantly increased active mouth opening compared with splint therapy, self-care, or medications.”
From Effectiveness of Manual Therapy and Therapeutic Exercise for Temporomandibular Disorders: Systematic Review and Meta-Analysis (2016) · cites this paper as [90]
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References 12 · Cited by 110
- Authors
- Minakuchi, H., Kuboki, T., Matsuka, Y., Maekawa, K., Yatani, H., & Yamashita, A.
- Affiliations
- Okayama University (JP)
- Corresponding author
- Minakuchi, H.
- Venue
- Journal of Dental Research
- Publisher
- SAGE Publications
- Published
- 2001-03
- Volume
- 80
- Issue
- 3
- Pages
- 924-928
- ISSN
- 0022-0345 (ISSN-L)
- 1544-0591
- OpenAlex
- W2172128330
- Cited by
- 110
- References
- 12
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 2 · 2023: 3 · 2022: 8 · 2021: 5 · 2020: 6 · 2019: 6 · 2018: 4 · 2017: 8 · 2016: 9 · 2015: 4 · 2014: 4 · 2013: 7 · 2012: 4
- FWCI
- 1.42
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Dental Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- University of California, Los Angeles
- Topics
- Health Sciences › Health Professions › Complementary and Manual Therapy › Temporomandibular Joint Disorders
- Health Sciences › Dentistry › Orthodontics › Orthodontics and Dentofacial Orthopedics
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Keywords
- temporomandibular disorders, conservative treatment, occlusal appliances, nonsteroidal anti-inflammatory drugs, self-care, maximum mouth opening, pain, activity limitation, treatment comparison
- MeSH terms
- Activities of Daily Living, Adult, Analysis of Variance, Anti-Inflammatory Agents, Non-Steroidal, Dental Occlusion, Centric, Diclofenac, Joint Dislocations, Exercise Therapy, Female, Follow-Up Studies, Humans, Male, Mandible, Mastication, Movement, Pain Measurement, Self Care, Temporomandibular Joint, Range of Motion, Articular, Treatment Outcome, Occlusal Splints, Statistics, Nonparametric, Temporomandibular Joint Disc
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