The DOI matches its Crossref record; 89 of the 89 references it cites were found in a registry or an index.
Fluoride’s Effects on the Formation of Teeth and Bones, and the Influence of Genetics
Open accessAbstract
Fluorides are present in the environment. Excessive systemic exposure to fluorides can lead to disturbances of bone homeostasis (skeletal fluorosis) and enamel development (dental/enamel fluorosis). The severity of dental fluorosis is also dependent upon fluoride dose and the timing and duration of fluoride exposure. Fluoride’s actions on bone cells predominate as anabolic effects both in vitro and in vivo. More recently, fluoride has been shown to induce osteoclastogenesis in mice. Fluorides appear to mediate their actions through the MAPK signaling pathway and can lead to changes in gene expression, cell stress, and cell death. Different strains of inbred mice demonstrate differential physiological responses to ingested fluoride. Genetic studies in mice are capable of identifying and characterizing fluoride-responsive genetic variations. Ultimately, this can lead to the identification of at-risk human populations who are susceptible to the unwanted or potentially adverse effects of fluoride action and to the elucidation of fundamental mechanisms by which fluoride affects biomineralization.
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Dental Enamel Formation and Implications for Oral Health and Disease
Lacruz, R. S., Habelitz, S., Wright, J. T., & Paine, M. L. (2017) · Physiological Reviews · doi:10.1152/physrev.00030.2016 · Cited by 599
Chemical Aspects of Human and Environmental Overload with Fluorine
Han, J., Kiss, L., Mei, H., Remete, A. M., Ponikvar-Svet, M., Sedgwick, D. M., Roman, R., Fustero, S., Moriwaki, H., & Soloshonok, V. A. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c01263 · Cited by 537
The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue
Ciosek, Ż., Kot, K., Kosik-Bogacka, D., Łanocha-Arendarczyk, N., & Rotter, I. (2021) · Biomolecules · doi:10.3390/biom11040506 · Cited by 389
The elements of life and medicines
Chellan, P., & Sadler, P. J. (2015) · Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences · doi:10.1098/rsta.2014.0182 · Cited by 274
Fluoride and human health: systematic appraisal of sources, exposures, metabolism, and toxicity
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Metadata
- Authors
- Everett, E. T.
- Venue
- Journal of Dental Research
- Publisher
- SAGE Publications
- Published
- 2010-10-06
- Volume
- 90
- Issue
- 5
- Pages
- 552-560
- ISSN
- 0022-0345 (ISSN-L)
- 1544-0591
- OpenAlex
- W2159933576
- Cited by
- 408
- References
- 89
- FWCI
- 6.36
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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