Home-based treadmill training for individuals with Parkinson's disease: a randomized controlled pilot trial
Abstract
OBJECTIVE: To investigate the feasibility and effectiveness of six weeks of home-based treadmill training in people with mild Parkinson's disease. DESIGN: Pilot randomized controlled trial of a six-week intervention followed by a further six weeks follow-up. SETTING: Home-based treadmill training with outcome measures taken at a hospital clinic. PARTICIPANTS: Twenty cognitively intact participants with mild Parkinson's disease and gait disturbance. Two participants from the treadmill training group and one from the control group dropped out. INTERVENTIONS: The treadmill training group undertook a semi-supervised home-based programme of treadmill walking for 20-40 minutes, four times a week for six weeks. The control group received usual care. MAIN OUTCOME MEASURES: The feasibility of the intervention was assessed by recording exercise adherence and acceptability, exercise intensity, fatigue, muscle soreness and adverse events. The primary outcome measure of efficacy was walking capacity (6-minute walk test distance). RESULTS: Home-based treadmill training was feasible, acceptable and safe with participants completing 78% (SD 36) of the prescribed training sessions. The treadmill training group did not improve their walking capacity compared to the control group. The treadmill training group showed a greater improvement than the control group in fatigue at post test (P = 0.04) and in quality of life at six weeks follow-up testing (P = 0.02). CONCLUSIONS: Semi-supervised home-based treadmill training is a feasible and safe form of exercise for cognitively intact people with mild Parkinson's disease. Further investigation regarding the effectiveness of home-based treadmill training is warranted.
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Differences in amount of feedback and cognitive engagement during practice may explain discrepant gait outcomes among treadmill studies.
“One possible explanation for this discrepancy in gait outcomes may be due to differences in the amount of feedback and cognitive engagement during practice 26, 27.”
From Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease (2013) · cites this paper as [26]
A few treadmill studies have shown no significant improvement in gait capacity despite similar practice.
“While the majority of treadmill studies have reported these benefits, a few studies have shown that despite a similar period of practice, no significant improvement in gait capacity occurred.”
From Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease (2013) · cites this paper as [26]
The reported training duration is in line with earlier reported adherence of approximately 80% in home-based PD interventions.
“Also, the reported training duration is in line with earlier reported adherence of approximately 80% in home-based PD interventions [41, 42].”
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References 34 · Cited by 108
- Authors
- Canning, C. G., Allen, N. E., Dean, C. M., Goh, L., & Fung, V. S.
- Affiliations
- The University of Sydney (AU)
- St George Hospital (AU)
- Venue
- Clinical Rehabilitation
- Publisher
- SAGE Publications
- Published
- 2012-01-18
- Volume
- 26
- Issue
- 9
- Pages
- 817-826
- ISSN
- 0269-2155 (ISSN-L)
- 1477-0873
- OpenAlex
- W2169173569
- Cited by
- 108
- References
- 34
- Citations by year
- 2026: 6 · 2025: 7 · 2024: 8 · 2023: 5 · 2022: 10 · 2021: 8 · 2020: 9 · 2019: 7 · 2018: 5 · 2017: 5 · 2016: 7 · 2015: 13 · 2014: 4 · 2013: 8 · 2012: 4
- FWCI
- 23.10
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Rehabilitation (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
- Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Keywords
- Parkinson's disease, home-based exercise, treadmill training, gait disturbance, walking capacity, 6-minute walk test, exercise adherence, fatigue, quality of life, feasibility
- MeSH terms
- Exercise Therapy, Feasibility Studies, Female, Home Care Services, Humans, Male, Middle Aged, New South Wales, Parkinson Disease, Pilot Projects, Walking, Outcome Assessment, Health Care, Gait Disorders, Neurologic
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